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Pathogenic DDX3X Mutations Impair RNA Metabolism and Neurogenesis during Fetal Cortical Development.
Lennox AL, Hoye ML, Jiang R, Johnson-Kerner BL, Suit LA, Venkataramanan S, Sheehan CJ, Alsina FC, Fregeau B, Aldinger KA, Moey C, Lobach I, Afenjar A, Babovic-Vuksanovic D, Bézieau S, Blackburn PR, Bunt J, Burglen L, Campeau PM, Charles P, Chung BHY, Cogné B, Curry C, D'Agostino MD, Di Donato N, Faivre L, Héron D, Innes AM, Isidor B, Keren B, Kimball A, Klee EW, Kuentz P, Küry S, Martin-Coignard D, Mirzaa G, Mignot C, Miyake N, Matsumoto N, Fujita A, Nava C, Nizon M, Rodriguez D, Blok LS, Thauvin-Robinet C, Thevenon J, Vincent M, Ziegler A, Dobyns W, Richards LJ, Barkovich AJ, Floor SN, Silver DL, Sherr EH. Lennox AL, et al. Among authors: floor sn. Neuron. 2020 May 6;106(3):404-420.e8. doi: 10.1016/j.neuron.2020.01.042. Epub 2020 Mar 4. Neuron. 2020. PMID: 32135084 Free PMC article.
Dual targeting of DDX3 and eIF4A by the translation inhibitor rocaglamide A.
Chen M, Asanuma M, Takahashi M, Shichino Y, Mito M, Fujiwara K, Saito H, Floor SN, Ingolia NT, Sodeoka M, Dodo K, Ito T, Iwasaki S. Chen M, et al. Among authors: floor sn. Cell Chem Biol. 2021 Apr 15;28(4):475-486.e8. doi: 10.1016/j.chembiol.2020.11.008. Epub 2020 Dec 8. Cell Chem Biol. 2021. PMID: 33296667 Free PMC article.
Control of ribosomal protein synthesis by the Microprocessor complex.
Jiang X, Prabhakar A, Van der Voorn SM, Ghatpande P, Celona B, Venkataramanan S, Calviello L, Lin C, Wang W, Black BL, Floor SN, Lagna G, Hata A. Jiang X, et al. Among authors: floor sn. Sci Signal. 2021 Feb 23;14(671):eabd2639. doi: 10.1126/scisignal.abd2639. Sci Signal. 2021. PMID: 33622983 Free PMC article.
DDX3 depletion represses translation of mRNAs with complex 5' UTRs.
Calviello L, Venkataramanan S, Rogowski KJ, Wyler E, Wilkins K, Tejura M, Thai B, Krol J, Filipowicz W, Landthaler M, Floor SN. Calviello L, et al. Among authors: floor sn. Nucleic Acids Res. 2021 May 21;49(9):5336-5350. doi: 10.1093/nar/gkab287. Nucleic Acids Res. 2021. PMID: 33905506 Free PMC article.
DDX3X and DDX3Y are redundant in protein synthesis.
Venkataramanan S, Gadek M, Calviello L, Wilkins K, Floor SN. Venkataramanan S, et al. Among authors: floor sn. RNA. 2021 Dec;27(12):1577-1588. doi: 10.1261/rna.078926.121. Epub 2021 Sep 17. RNA. 2021. PMID: 34535544 Free PMC article.
44 results