Fleming KD - Search Results

1

Structural insights into perilipin 3 membrane association in response to diacylglycerol accumulation.

Choi YM, Ajjaji D, Fleming KD, Borbat PP, Jenkins ML, Moeller BE, Fernando S, Bhatia SR, Freed JH, Burke JE, Thiam AR, Airola MV. Choi YM, et al. Among authors: fleming kd. Nat Commun. 2023 Jun 2;14(1):3204. doi: 10.1038/s41467-023-38725-w. Nat Commun. 2023. PMID: 37268630 Free PMC article.

2

The middle lipin domain adopts a membrane-binding dimeric protein fold.

Gu W, Gao S, Wang H, Fleming KD, Hoffmann RM, Yang JW, Patel NM, Choi YM, Burke JE, Reue K, Airola MV. Gu W, et al. Among authors: fleming kd. Nat Commun. 2021 Aug 5;12(1):4718. doi: 10.1038/s41467-021-24929-5. Nat Commun. 2021. PMID: 34354069 Free PMC article.

3

[No title available]

[No authors listed] [No authors listed] PMID: 35554488

4

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation.

Levina A, Fleming KD, Burke JE, Leonard TA. Levina A, et al. Among authors: fleming kd. Nat Commun. 2022 Apr 6;13(1):1874. doi: 10.1038/s41467-022-29368-4. Nat Commun. 2022. PMID: 35387990 Free PMC article.

5

The substrate specificity of the human TRAPPII complex's Rab-guanine nucleotide exchange factor activity.

Jenkins ML, Harris NJ, Dalwadi U, Fleming KD, Ziemianowicz DS, Rafiei A, Martin EM, Schriemer DC, Yip CK, Burke JE. Jenkins ML, et al. Among authors: fleming kd. Commun Biol. 2020 Dec 4;3(1):735. doi: 10.1038/s42003-020-01459-2. Commun Biol. 2020. PMID: 33277614 Free PMC article.

6

Molecular basis for differential activation of p101 and p84 complexes of PI3Kγ by Ras and GPCRs.

Rathinaswamy MK, Jenkins ML, Duewell BR, Zhang X, Harris NJ, Evans JT, Stariha JTB, Dalwadi U, Fleming KD, Ranga-Prasad H, Yip CK, Williams RL, Hansen SD, Burke JE. Rathinaswamy MK, et al. Among authors: fleming kd. Cell Rep. 2023 Mar 28;42(3):112172. doi: 10.1016/j.celrep.2023.112172. Epub 2023 Feb 26. Cell Rep. 2023. PMID: 36842083 Free PMC article.

7

Biochemical Characterization of the TINTIN Module of the NuA4 Complex Reveals Allosteric Regulation of Nucleosome Interaction.

Dalwadi U, Corrado E, Fleming KD, Moeller BE, Nam SE, Burke JE, Yip CK. Dalwadi U, et al. Among authors: fleming kd. Mol Cell Biol. 2022 Nov 17;42(11):e0017022. doi: 10.1128/mcb.00170-22. Epub 2022 Oct 3. Mol Cell Biol. 2022. PMID: 36190236 Free PMC article.

8

Rathinaswamy MK, Gaieb Z, Fleming KD, Borsari C, Harris NJ, Moeller BE, Wymann MP, Amaro RE, Burke JE. Rathinaswamy MK, et al. Among authors: fleming kd. Elife. 2021 Mar 4;10:e64691. doi: 10.7554/eLife.64691. Elife. 2021. PMID: 33661099 Free PMC article.

9

Biochemical Insight into Novel Rab-GEF Activity of the Mammalian TRAPPIII Complex.

Harris NJ, Jenkins ML, Dalwadi U, Fleming KD, Nam SE, Parson MAH, Yip CK, Burke JE. Harris NJ, et al. Among authors: fleming kd. J Mol Biol. 2021 Sep 3;433(18):167145. doi: 10.1016/j.jmb.2021.167145. Epub 2021 Jul 3. J Mol Biol. 2021. PMID: 34229011

10

HDX-MS-optimized approach to characterize nanobodies as tools for biochemical and structural studies of class IB phosphoinositide 3-kinases.

Rathinaswamy MK, Fleming KD, Dalwadi U, Pardon E, Harris NJ, Yip CK, Steyaert J, Burke JE. Rathinaswamy MK, et al. Among authors: fleming kd. Structure. 2021 Dec 2;29(12):1371-1381.e6. doi: 10.1016/j.str.2021.07.002. Epub 2021 Aug 3. Structure. 2021. PMID: 34348129 Free article.

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