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Intelectin-1 binds and alters the localization of the mucus barrier-modifying bacterium Akkermansia muciniphila.
Matute JD, Duan J, Flak MB, Griebel P, Tascon-Arcila JA, Doms S, Hanley T, Antanaviciute A, Gundrum J, Mark Welch JL, Sit B, Abtahi S, Fuhler GM, Grootjans J, Tran F, Stengel ST, White JR, Krupka N, Haller D, Clare S, Lawley TD, Kaser A, Simmons A, Glickman JN, Bry L, Rosenstiel P, Borisy G, Waldor MK, Baines JF, Turner JR, Blumberg RS. Matute JD, et al. Among authors: flak mb. J Exp Med. 2023 Jan 2;220(1):e20211938. doi: 10.1084/jem.20211938. Epub 2022 Nov 22. J Exp Med. 2023. PMID: 36413219 Free PMC article.
Intestinal epithelial cell endoplasmic reticulum stress promotes MULT1 up-regulation and NKG2D-mediated inflammation.
Hosomi S, Grootjans J, Tschurtschenthaler M, Krupka N, Matute JD, Flak MB, Martinez-Naves E, Gomez Del Moral M, Glickman JN, Ohira M, Lanier LL, Kaser A, Blumberg R. Hosomi S, et al. Among authors: flak mb. J Exp Med. 2017 Oct 2;214(10):2985-2997. doi: 10.1084/jem.20162041. Epub 2017 Jul 26. J Exp Med. 2017. PMID: 28747426 Free PMC article.
Defective ATG16L1-mediated removal of IRE1α drives Crohn's disease-like ileitis.
Tschurtschenthaler M, Adolph TE, Ashcroft JW, Niederreiter L, Bharti R, Saveljeva S, Bhattacharyya J, Flak MB, Shih DQ, Fuhler GM, Parkes M, Kohno K, Iwawaki T, Janneke van der Woude C, Harding HP, Smith AM, Peppelenbosch MP, Targan SR, Ron D, Rosenstiel P, Blumberg RS, Kaser A. Tschurtschenthaler M, et al. Among authors: flak mb. J Exp Med. 2017 Feb;214(2):401-422. doi: 10.1084/jem.20160791. Epub 2017 Jan 12. J Exp Med. 2017. PMID: 28082357 Free PMC article.
ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells.
Niederreiter L, Fritz TM, Adolph TE, Krismer AM, Offner FA, Tschurtschenthaler M, Flak MB, Hosomi S, Tomczak MF, Kaneider NC, Sarcevic E, Kempster SL, Raine T, Esser D, Rosenstiel P, Kohno K, Iwawaki T, Tilg H, Blumberg RS, Kaser A. Niederreiter L, et al. Among authors: flak mb. J Exp Med. 2013 Sep 23;210(10):2041-56. doi: 10.1084/jem.20122341. Epub 2013 Sep 16. J Exp Med. 2013. PMID: 24043762 Free PMC article.
Immunology. Welcome to the microgenderome.
Flak MB, Neves JF, Blumberg RS. Flak MB, et al. Science. 2013 Mar 1;339(6123):1044-5. doi: 10.1126/science.1236226. Science. 2013. PMID: 23449586 Free PMC article.
Paneth cells as a site of origin for intestinal inflammation.
Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS. Adolph TE, et al. Among authors: flak mb. Nature. 2013 Nov 14;503(7475):272-6. doi: 10.1038/nature12599. Epub 2013 Oct 2. Nature. 2013. PMID: 24089213 Free PMC article.
The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction.
Chen L, Chen Z, Baker K, Halvorsen EM, da Cunha AP, Flak MB, Gerber G, Huang YH, Hosomi S, Arthur JC, Dery KJ, Nagaishi T, Beauchemin N, Holmes KV, Ho JW, Shively JE, Jobin C, Onderdonk AB, Bry L, Weiner HL, Higgins DE, Blumberg RS. Chen L, et al. Among authors: flak mb. Immunity. 2012 Nov 16;37(5):930-46. doi: 10.1016/j.immuni.2012.07.016. Epub 2012 Nov 1. Immunity. 2012. PMID: 23123061 Free PMC article.
19 results