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DICAM promotes TH17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation.
Charabati M, Grasmuck C, Ghannam S, Bourbonnière L, Fournier AP, Lécuyer MA, Tastet O, Kebir H, Rébillard RM, Hoornaert C, Gowing E, Larouche S, Fortin O, Pittet C, Filali-Mouhim A, Lahav B, Moumdjian R, Bouthillier A, Girard M, Duquette P, Cayrol R, Peelen E, Quintana FJ, Antel JP, Flügel A, Larochelle C, Arbour N, Zandee S, Prat A. Charabati M, et al. Among authors: flugel a. Sci Transl Med. 2022 Jan 5;14(626):eabj0473. doi: 10.1126/scitranslmed.abj0473. Epub 2022 Jan 5. Sci Transl Med. 2022. PMID: 34985970
Laquinimod enhances central nervous system barrier functions.
Lühder F, Kebir H, Odoardi F, Litke T, Sonneck M, Alvarez JI, Winchenbach J, Eckert N, Hayardeny L, Sorani E, Lodygin D, Flügel A, Prat A. Lühder F, et al. Among authors: flugel a. Neurobiol Dis. 2017 Jun;102:60-69. doi: 10.1016/j.nbd.2017.02.002. Epub 2017 Feb 22. Neurobiol Dis. 2017. PMID: 28235673
The lung microbiome regulates brain autoimmunity.
Hosang L, Canals RC, van der Flier FJ, Hollensteiner J, Daniel R, Flügel A, Odoardi F. Hosang L, et al. Among authors: flugel a. Nature. 2022 Mar;603(7899):138-144. doi: 10.1038/s41586-022-04427-4. Epub 2022 Feb 23. Nature. 2022. PMID: 35197636
T cells become licensed in the lung to enter the central nervous system.
Odoardi F, Sie C, Streyl K, Ulaganathan VK, Schläger C, Lodygin D, Heckelsmiller K, Nietfeld W, Ellwart J, Klinkert WE, Lottaz C, Nosov M, Brinkmann V, Spang R, Lehrach H, Vingron M, Wekerle H, Flügel-Koch C, Flügel A. Odoardi F, et al. Among authors: flugel koch c, flugel a. Nature. 2012 Aug 30;488(7413):675-9. doi: 10.1038/nature11337. Nature. 2012. PMID: 22914092
Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses.
Schweingruber N, Fischer HJ, Fischer L, van den Brandt J, Karabinskaya A, Labi V, Villunger A, Kretzschmar B, Huppke P, Simons M, Tuckermann JP, Flügel A, Lühder F, Reichardt HM. Schweingruber N, et al. Among authors: flugel a. Acta Neuropathol. 2014 May;127(5):713-29. doi: 10.1007/s00401-014-1248-4. Epub 2014 Feb 1. Acta Neuropathol. 2014. PMID: 24488308 Free PMC article.
Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid.
Schläger C, Körner H, Krueger M, Vidoli S, Haberl M, Mielke D, Brylla E, Issekutz T, Cabañas C, Nelson PJ, Ziemssen T, Rohde V, Bechmann I, Lodygin D, Odoardi F, Flügel A. Schläger C, et al. Among authors: flugel a. Nature. 2016 Feb 18;530(7590):349-53. doi: 10.1038/nature16939. Epub 2016 Feb 10. Nature. 2016. PMID: 26863192
94 results