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Page 1
Meningeal inflammation and cortical demyelination in acute multiple sclerosis.
Bevan RJ, Evans R, Griffiths L, Watkins LM, Rees MI, Magliozzi R, Allen I, McDonnell G, Kee R, Naughton M, Fitzgerald DC, Reynolds R, Neal JW, Howell OW. Bevan RJ, et al. Among authors: fitzgerald dc. Ann Neurol. 2018 Dec;84(6):829-842. doi: 10.1002/ana.25365. Epub 2018 Nov 30. Ann Neurol. 2018. PMID: 30362156 Free article.
CCN3 is dynamically regulated by treatment and disease state in multiple sclerosis.
Naughton M, Moffat J, Eleftheriadis G, de la Vega Gallardo N, Young A, Falconer J, Hawkins K, Pearson B, Perbal B, Hogan A, Moynagh P, Loveless S, Robertson NP, Gran B, Kee R, Hughes S, McDonnell G, Howell O, Fitzgerald DC. Naughton M, et al. Among authors: fitzgerald dc. J Neuroinflammation. 2020 Nov 22;17(1):349. doi: 10.1186/s12974-020-02025-7. J Neuroinflammation. 2020. PMID: 33222687 Free PMC article.
Dynamic CCN3 expression in the murine CNS does not confer essential roles in myelination or remyelination.
de la Vega Gallardo N, Penalva R, Dittmer M, Naughton M, Falconer J, Moffat J, de la Fuente AG, Hombrebueno JR, Lin Z, Perbal B, Ingram RJ, Evergren E, Fitzgerald DC. de la Vega Gallardo N, et al. Among authors: fitzgerald dc. Proc Natl Acad Sci U S A. 2020 Jul 28;117(30):18018-18028. doi: 10.1073/pnas.1922089117. Epub 2020 Jul 10. Proc Natl Acad Sci U S A. 2020. PMID: 32651278 Free PMC article.
Regulatory T cells promote myelin regeneration in the central nervous system.
Dombrowski Y, O'Hagan T, Dittmer M, Penalva R, Mayoral SR, Bankhead P, Fleville S, Eleftheriadis G, Zhao C, Naughton M, Hassan R, Moffat J, Falconer J, Boyd A, Hamilton P, Allen IV, Kissenpfennig A, Moynagh PN, Evergren E, Perbal B, Williams AC, Ingram RJ, Chan JR, Franklin RJM, Fitzgerald DC. Dombrowski Y, et al. Among authors: fitzgerald dc. Nat Neurosci. 2017 May;20(5):674-680. doi: 10.1038/nn.4528. Epub 2017 Mar 13. Nat Neurosci. 2017. PMID: 28288125 Free PMC article.
Microglia Require CD4 T Cells to Complete the Fetal-to-Adult Transition.
Pasciuto E, Burton OT, Roca CP, Lagou V, Rajan WD, Theys T, Mancuso R, Tito RY, Kouser L, Callaerts-Vegh Z, de la Fuente AG, Prezzemolo T, Mascali LG, Brajic A, Whyte CE, Yshii L, Martinez-Muriana A, Naughton M, Young A, Moudra A, Lemaitre P, Poovathingal S, Raes J, De Strooper B, Fitzgerald DC, Dooley J, Liston A. Pasciuto E, et al. Among authors: fitzgerald dc. Cell. 2020 Aug 6;182(3):625-640.e24. doi: 10.1016/j.cell.2020.06.026. Epub 2020 Jul 22. Cell. 2020. PMID: 32702313 Free PMC article.
Inflammation in multiple sclerosis induces a specific reactive astrocyte state driving non-cell-autonomous neuronal damage.
Matute-Blanch C, Brito V, Midaglia L, Villar LM, Garcia-Diaz Barriga G, Guzman de la Fuente A, Borrás E, Fernández-García S, Calvo-Barreiro L, Miguez A, Costa-Frossard L, Pinteac R, Sabidó E, Alberch J, Fitzgerald DC, Montalban X, Comabella M. Matute-Blanch C, et al. Among authors: fitzgerald dc. Clin Transl Med. 2022 May;12(5):e837. doi: 10.1002/ctm2.837. Clin Transl Med. 2022. PMID: 35538884 Free PMC article. No abstract available.
The microbiota regulates murine inflammatory responses to toxin-induced CNS demyelination but has minimal impact on remyelination.
McMurran CE, Guzman de la Fuente A, Penalva R, Ben Menachem-Zidon O, Dombrowski Y, Falconer J, Gonzalez GA, Zhao C, Krause FN, Young AMH, Griffin JL, Jones CA, Hollins C, Heimesaat MM, Fitzgerald DC, Franklin RJM. McMurran CE, et al. Among authors: fitzgerald dc. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25311-25321. doi: 10.1073/pnas.1905787116. Epub 2019 Nov 18. Proc Natl Acad Sci U S A. 2019. PMID: 31740610 Free PMC article.
CNS Remyelination and the Innate Immune System.
McMurran CE, Jones CA, Fitzgerald DC, Franklin RJ. McMurran CE, et al. Among authors: fitzgerald dc. Front Cell Dev Biol. 2016 May 3;4:38. doi: 10.3389/fcell.2016.00038. eCollection 2016. Front Cell Dev Biol. 2016. PMID: 27200350 Free PMC article. Review.
111 results