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Discovery of the development candidate N-tert-butyl nodulisporamide: a safe and efficacious once monthly oral agent for the control of fleas and ticks on companion animals.
Meinke PT, Colletti SL, Fisher MH, Wyvratt MJ, Shih TL, Ayer MB, Li C, Lim J, Ok D, Salva S, Warmke LM, Zakson M, Michael BF, Demontigny P, Ostlind DA, Fink D, Drag M, Schmatz DM, Shoop WL. Meinke PT, et al. Among authors: fisher mh. J Med Chem. 2009 Jun 11;52(11):3505-15. doi: 10.1021/jm801334v. J Med Chem. 2009. PMID: 19445514
Nodulisporic acid side-chain modifications: access to the 2", 3", 4", and 6" registers.
Chakravarty PK, Shih TL, Colletti SL, Ayer MB, Snedden C, Kuo H, Tyagarajan S, Gregory L, Zakson-Aiken M, Shoop WL, Schmatz DM, Wyvratt M, Fisher MH, Meinke PT. Chakravarty PK, et al. Among authors: fisher mh. Bioorg Med Chem Lett. 2003 Jan 6;13(1):147-50. doi: 10.1016/s0960-894x(02)00826-0. Bioorg Med Chem Lett. 2003. PMID: 12467636
Systemic efficacy of nodulisporamides against fleas on dogs.
Shoop WL, Zakson-Aiken M, Gregory LM, Michael BF, Pivnichny J, Meinke PT, Fisher MH, Wyvratt MJ, Pikounis B, Schmatz DM. Shoop WL, et al. Among authors: fisher mh. J Parasitol. 2001 Oct;87(5):1150-4. doi: 10.1645/0022-3395(2001)087[1150:SEONAF]2.0.CO;2. J Parasitol. 2001. PMID: 11695382
Synthesis of nodulisporic acid 2' '-oxazoles and 2' '-thiazoles.
Berger R, Shoop WL, Pivnichny JV, Warmke LM, Zakson-Aiken M, Owens KA, deMontigny P, Schmatz DM, Wyvratt MJ, Fisher MH, Meinke PT, Colletti SL. Berger R, et al. Among authors: fisher mh. Org Lett. 2001 Nov 15;3(23):3715-8. doi: 10.1021/ol016651x. Org Lett. 2001. PMID: 11700120
Synthesis and SAR studies of very potent imidazopyridine antiprotozoal agents.
Biftu T, Feng D, Fisher M, Liang GB, Qian X, Scribner A, Dennis R, Lee S, Liberator PA, Brown C, Gurnett A, Leavitt PS, Thompson D, Mathew J, Misura A, Samaras S, Tamas T, Sina JF, McNulty KA, McKnight CG, Schmatz DM, Wyvratt M. Biftu T, et al. Bioorg Med Chem Lett. 2006 May 1;16(9):2479-83. doi: 10.1016/j.bmcl.2006.01.092. Epub 2006 Feb 7. Bioorg Med Chem Lett. 2006. PMID: 16464591
Synthesis and SAR studies of diarylpyrrole anticoccidial agents.
Qian X, Liang GB, Feng D, Fisher M, Crumley T, Rattray S, Dulski PM, Gurnett A, Leavitt PS, Liberator PA, Misura AS, Samaras S, Tamas T, Schmatz DM, Wyvratt M, Biftu T. Qian X, et al. Bioorg Med Chem Lett. 2006 May 15;16(10):2817-21. doi: 10.1016/j.bmcl.2006.01.041. Epub 2006 Mar 6. Bioorg Med Chem Lett. 2006. PMID: 16517161
157 results