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Very-late-antigen-4 (VLA-4)-mediated brain invasion by neutrophils leads to interactions with microglia, increased ischemic injury and impaired behavior in experimental stroke.
Neumann J, Riek-Burchardt M, Herz J, Doeppner TR, König R, Hütten H, Etemire E, Männ L, Klingberg A, Fischer T, Görtler MW, Heinze HJ, Reichardt P, Schraven B, Hermann DM, Reymann KG, Gunzer M. Neumann J, et al. Among authors: fischer t. Acta Neuropathol. 2015 Feb;129(2):259-77. doi: 10.1007/s00401-014-1355-2. Epub 2014 Nov 13. Acta Neuropathol. 2015. PMID: 25391494
Clinically relevant doses of FLT3-kinase inhibitors quizartinib and midostaurin do not impair T-cell reactivity and function.
Wolleschak D, Mack TS, Perner F, Frey S, Schnöder TM, Wagner MC, Höding C, Pils MC, Parkner A, Kliche S, Schraven B, Hebel K, Brunner-Weinzierl M, Ranjan S, Isermann B, Lipka DB, Fischer T, Heidel FH. Wolleschak D, et al. Among authors: fischer t. Haematologica. 2014 Jun;99(6):e90-3. doi: 10.3324/haematol.2014.104331. Epub 2014 Mar 14. Haematologica. 2014. PMID: 24633870 Free PMC article. No abstract available.
Activated protein C protects from GvHD via PAR2/PAR3 signalling in regulatory T-cells.
Ranjan S, Goihl A, Kohli S, Gadi I, Pierau M, Shahzad K, Gupta D, Bock F, Wang H, Shaikh H, Kähne T, Reinhold D, Bank U, Zenclussen AC, Niemz J, Schnöder TM, Brunner-Weinzierl M, Fischer T, Kalinski T, Schraven B, Luft T, Huehn J, Naumann M, Heidel FH, Isermann B. Ranjan S, et al. Among authors: fischer t. Nat Commun. 2017 Aug 21;8(1):311. doi: 10.1038/s41467-017-00169-4. Nat Commun. 2017. PMID: 28827518 Free PMC article.
JAK2-V617F promotes venous thrombosis through β1/β2 integrin activation.
Edelmann B, Gupta N, Schnoeder TM, Oelschlegel AM, Shahzad K, Goldschmidt J, Philipsen L, Weinert S, Ghosh A, Saalfeld FC, Nimmagadda SC, Müller P, Braun-Dullaeus R, Mohr J, Wolleschak D, Kliche S, Amthauer H, Heidel FH, Schraven B, Isermann B, Müller AJ, Fischer T. Edelmann B, et al. Among authors: fischer t. J Clin Invest. 2018 Oct 1;128(10):4359-4371. doi: 10.1172/JCI90312. Epub 2018 Jul 19. J Clin Invest. 2018. PMID: 30024857 Free PMC article.
Directional mast cell degranulation of tumor necrosis factor into blood vessels primes neutrophil extravasation.
Dudeck J, Kotrba J, Immler R, Hoffmann A, Voss M, Alexaki VI, Morton L, Jahn SR, Katsoulis-Dimitriou K, Winzer S, Kollias G, Fischer T, Nedospasov SA, Dunay IR, Chavakis T, Müller AJ, Schraven B, Sperandio M, Dudeck A. Dudeck J, et al. Among authors: fischer t. Immunity. 2021 Mar 9;54(3):468-483.e5. doi: 10.1016/j.immuni.2020.12.017. Epub 2021 Jan 22. Immunity. 2021. PMID: 33484643 Free article.
Genetic Knock-out of TNFR1 and TNFR2 in a JAK2-V617F Polycythemia Vera Mouse Model.
Müller P, Baldauf CK, Haage TR, Charakopoulos E, Böttcher M, Bhuria V, Mougiakakos D, Schraven B, Fischer T. Müller P, et al. Among authors: fischer t. Hemasphere. 2022 Apr 15;6(5):e717. doi: 10.1097/HS9.0000000000000717. eCollection 2022 May. Hemasphere. 2022. PMID: 35449791 Free PMC article. No abstract available.
Cell autonomous expression of CXCL-10 in JAK2V617F-mutated MPN.
Schnöder TM, Eberhardt J, Koehler M, Bierhoff HB, Weinert S, Pandey AD, Nimmagadda SC, Wolleschak D, Jöhrens K, Fischer T, Heidel FH. Schnöder TM, et al. Among authors: fischer t. J Cancer Res Clin Oncol. 2017 May;143(5):807-820. doi: 10.1007/s00432-017-2354-1. Epub 2017 Feb 23. J Cancer Res Clin Oncol. 2017. PMID: 28233092
2,224 results