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Extensively edited pigs.
Fischer K, Schnieke A. Fischer K, et al. Nat Biomed Eng. 2021 Feb;5(2):128-129. doi: 10.1038/s41551-021-00684-2. Nat Biomed Eng. 2021. PMID: 33580227 No abstract available.
Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing.
Fischer K, Kraner-Scheiber S, Petersen B, Rieblinger B, Buermann A, Flisikowska T, Flisikowski K, Christan S, Edlinger M, Baars W, Kurome M, Zakhartchenko V, Kessler B, Plotzki E, Szczerbal I, Switonski M, Denner J, Wolf E, Schwinzer R, Niemann H, Kind A, Schnieke A. Fischer K, et al. Sci Rep. 2016 Jun 29;6:29081. doi: 10.1038/srep29081. Sci Rep. 2016. PMID: 27353424 Free PMC article.
Porcine familial adenomatous polyposis model enables systematic analysis of early events in adenoma progression.
Flisikowska T, Stachowiak M, Xu H, Wagner A, Hernandez-Caceres A, Wurmser C, Perleberg C, Pausch H, Perkowska A, Fischer K, Frishman D, Fries R, Switonski M, Kind A, Saur D, Schnieke A, Flisikowski K. Flisikowska T, et al. Among authors: fischer k. Sci Rep. 2017 Jul 26;7(1):6613. doi: 10.1038/s41598-017-06741-8. Sci Rep. 2017. PMID: 28747659 Free PMC article.
Strong xenoprotective function by single-copy transgenes placed sequentially at a permissive locus.
Rieblinger B, Fischer K, Kind A, Saller BS, Baars W, Schuster M, Wolf-van Buerck L, Schäffler A, Flisikowska T, Kurome M, Zakhartchenko V, Kessler B, Flisikowski K, Wolf E, Seissler J, Schwinzer R, Schnieke A. Rieblinger B, et al. Among authors: fischer k. Xenotransplantation. 2018 Mar;25(2):e12382. doi: 10.1111/xen.12382. Epub 2018 Jan 23. Xenotransplantation. 2018. PMID: 29359453
Assembling multiple xenoprotective transgenes in pigs.
Fischer K, Kind A, Schnieke A. Fischer K, et al. Xenotransplantation. 2018 Nov;25(6):e12431. doi: 10.1111/xen.12431. Epub 2018 Jul 28. Xenotransplantation. 2018. PMID: 30055014 Review.
Viable pigs after simultaneous inactivation of porcine MHC class I and three xenoreactive antigen genes GGTA1, CMAH and B4GALNT2.
Fischer K, Rieblinger B, Hein R, Sfriso R, Zuber J, Fischer A, Klinger B, Liang W, Flisikowski K, Kurome M, Zakhartchenko V, Kessler B, Wolf E, Rieben R, Schwinzer R, Kind A, Schnieke A. Fischer K, et al. Among authors: fischer a. Xenotransplantation. 2020 Jan;27(1):e12560. doi: 10.1111/xen.12560. Epub 2019 Oct 8. Xenotransplantation. 2020. PMID: 31591751 Free article.
2,751 results