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Genome-wide CRISPR screens identify GATA6 as a proviral host factor for SARS-CoV-2 via modulation of ACE2.
Israeli M, Finkel Y, Yahalom-Ronen Y, Paran N, Chitlaru T, Israeli O, Cohen-Gihon I, Aftalion M, Falach R, Rotem S, Elia U, Nemet I, Kliker L, Mandelboim M, Beth-Din A, Israely T, Cohen O, Stern-Ginossar N, Bercovich-Kinori A. Israeli M, et al. Among authors: finkel y. Nat Commun. 2022 Apr 25;13(1):2237. doi: 10.1038/s41467-022-29896-z. Nat Commun. 2022. PMID: 35469023 Free PMC article.
The coding capacity of SARS-CoV-2.
Finkel Y, Mizrahi O, Nachshon A, Weingarten-Gabbay S, Morgenstern D, Yahalom-Ronen Y, Tamir H, Achdout H, Stein D, Israeli O, Beth-Din A, Melamed S, Weiss S, Israely T, Paran N, Schwartz M, Stern-Ginossar N. Finkel Y, et al. Nature. 2021 Jan;589(7840):125-130. doi: 10.1038/s41586-020-2739-1. Epub 2020 Sep 9. Nature. 2021. PMID: 32906143
SARS-CoV-2 uses a multipronged strategy to impede host protein synthesis.
Finkel Y, Gluck A, Nachshon A, Winkler R, Fisher T, Rozman B, Mizrahi O, Lubelsky Y, Zuckerman B, Slobodin B, Yahalom-Ronen Y, Tamir H, Ulitsky I, Israely T, Paran N, Schwartz M, Stern-Ginossar N. Finkel Y, et al. Nature. 2021 Jun;594(7862):240-245. doi: 10.1038/s41586-021-03610-3. Epub 2021 May 12. Nature. 2021. PMID: 33979833
Parsing the role of NSP1 in SARS-CoV-2 infection.
Fisher T, Gluck A, Narayanan K, Kuroda M, Nachshon A, Hsu JC, Halfmann PJ, Yahalom-Ronen Y, Tamir H, Finkel Y, Schwartz M, Weiss S, Tseng CK, Israely T, Paran N, Kawaoka Y, Makino S, Stern-Ginossar N. Fisher T, et al. Among authors: finkel y. Cell Rep. 2022 Jun 14;39(11):110954. doi: 10.1016/j.celrep.2022.110954. Epub 2022 May 26. Cell Rep. 2022. PMID: 35671758 Free PMC article.
Viral Short ORFs and Their Possible Functions.
Finkel Y, Stern-Ginossar N, Schwartz M. Finkel Y, et al. Proteomics. 2018 May;18(10):e1700255. doi: 10.1002/pmic.201700255. Epub 2018 Jan 19. Proteomics. 2018. PMID: 29150926 Free PMC article. Review.
Profiling SARS-CoV-2 HLA-I peptidome reveals T cell epitopes from out-of-frame ORFs.
Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Gallagher KME, Bauer MR, Taylor HB, Dunn WA, Tarr C, Sidney J, Rachimi S, Conway HL, Katsis K, Wang Y, Leistritz-Edwards D, Durkin MR, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Carulli IP, Chea VA, Chandrashekar A, Bozkus CC, Carrington M; MGH COVID-19 Collection & Processing Team; Bhardwaj N, Barouch DH, Sette A, Maus MV, Rice CM, Clauser KR, Keskin DB, Pregibon DC, Hacohen N, Carr SA, Abelin JG, Saeed M, Sabeti PC. Weingarten-Gabbay S, et al. Among authors: finkel y. Cell. 2021 Jul 22;184(15):3962-3980.e17. doi: 10.1016/j.cell.2021.05.046. Epub 2021 Jun 3. Cell. 2021. PMID: 34171305 Free PMC article.
SARS-CoV-2 infected cells present HLA-I peptides from canonical and out-of-frame ORFs.
Weingarten-Gabbay S, Klaeger S, Sarkizova S, Pearlman LR, Chen DY, Bauer MR, Taylor HB, Conway HL, Tomkins-Tinch CH, Finkel Y, Nachshon A, Gentili M, Rivera KD, Keskin DB, Rice CM, Clauser KR, Hacohen N, Carr SA, Abelin JG, Saeed M, Sabeti PC. Weingarten-Gabbay S, et al. Among authors: finkel y. bioRxiv [Preprint]. 2020 Oct 26:2020.10.02.324145. doi: 10.1101/2020.10.02.324145. bioRxiv. 2020. PMID: 33024965 Free PMC article. Preprint.
Parsing the role of NSP1 in SARS-CoV-2 infection.
Fisher T, Gluck A, Narayanan K, Kuroda M, Nachshon A, Hsu JC, Halfmann PJ, Yahalom-Ronen Y, Finkel Y, Schwartz M, Weiss S, Tseng CK, Israely T, Paran N, Kawaoka Y, Makino S, Stern-Ginossar N. Fisher T, et al. Among authors: finkel y. bioRxiv [Preprint]. 2022 Mar 16:2022.03.14.484208. doi: 10.1101/2022.03.14.484208. bioRxiv. 2022. PMID: 35313595 Free PMC article. Updated. Preprint.
101 results