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Acetyl-leucine slows disease progression in lysosomal storage disorders.
Kaya E, Smith DA, Smith C, Morris L, Bremova-Ertl T, Cortina-Borja M, Fineran P, Morten KJ, Poulton J, Boland B, Spencer J, Strupp M, Platt FM. Kaya E, et al. Among authors: fineran p. Brain Commun. 2020 Dec 20;3(1):fcaa148. doi: 10.1093/braincomms/fcaa148. eCollection 2021. Brain Commun. 2020. PMID: 33738443 Free PMC article.
Annual severity increment score as a tool for stratifying patients with Niemann-Pick disease type C and for recruitment to clinical trials.
Cortina-Borja M, Te Vruchte D, Mengel E, Amraoui Y, Imrie J, Jones SA, I Dali C, Fineran P, Kirkegaard T, Runz H, Lachmann R, Bremova-Ertl T, Strupp M, Platt FM. Cortina-Borja M, et al. Among authors: fineran p. Orphanet J Rare Dis. 2018 Aug 16;13(1):143. doi: 10.1186/s13023-018-0880-9. Orphanet J Rare Dis. 2018. PMID: 30115089 Free PMC article.
Pathogenic mycobacteria achieve cellular persistence by inhibiting the Niemann-Pick Type C disease cellular pathway.
Fineran P, Lloyd-Evans E, Lack NA, Platt N, Davis LC, Morgan AJ, Höglinger D, Tatituri RVV, Clark S, Williams IM, Tynan P, Al Eisa N, Nazarova E, Williams A, Galione A, Ory DS, Besra GS, Russell DG, Brenner MB, Sim E, Platt FM. Fineran P, et al. Wellcome Open Res. 2016 Nov 18;1:18. doi: 10.12688/wellcomeopenres.10036.2. Wellcome Open Res. 2016. PMID: 28008422 Free PMC article.
Measuring the phagocytic activity of cells.
Platt N, Fineran P. Platt N, et al. Among authors: fineran p. Methods Cell Biol. 2015;126:287-304. doi: 10.1016/bs.mcb.2014.10.025. Epub 2015 Jan 14. Methods Cell Biol. 2015. PMID: 25665451
RNA targeting and cleavage by the type III-Dv CRISPR effector complex.
Schwartz EA, Bravo JPK, Ahsan M, Macias LA, McCafferty CL, Dangerfield TL, Walker JN, Brodbelt JS, Palermo G, Fineran PC, Fagerlund RD, Taylor DW. Schwartz EA, et al. Among authors: fineran pc. Nat Commun. 2024 Apr 18;15(1):3324. doi: 10.1038/s41467-024-47506-y. Nat Commun. 2024. PMID: 38637512 Free PMC article.
Cytokeratin-18 is a sensitive biomarker of alanine transaminase increase in a placebo-controlled, randomized, crossover trial of therapeutic paracetamol dosing (PATH-BP biomarker Sub-study).
Scullion KM, MacIntyre IM, Sloan-Dennison S, Clark B, Fineran P, Mair J, Creasey D, Rathmell C, Faulds K, Graham D, Webb DJ, Dear JW. Scullion KM, et al. Among authors: fineran p. Toxicol Sci. 2024 Mar 23:kfae031. doi: 10.1093/toxsci/kfae031. Online ahead of print. Toxicol Sci. 2024. PMID: 38521541
Gram-negative endolysins: overcoming the outer membrane obstacle.
Sisson HM, Jackson SA, Fagerlund RD, Warring SL, Fineran PC. Sisson HM, et al. Among authors: fineran pc. Curr Opin Microbiol. 2024 Apr;78:102433. doi: 10.1016/j.mib.2024.102433. Epub 2024 Feb 12. Curr Opin Microbiol. 2024. PMID: 38350268 Free article. Review.
135 results