Filippova GN - Search Results

1

CTCF haploinsufficiency destabilizes DNA methylation and predisposes to cancer.

Kemp CJ, Moore JM, Moser R, Bernard B, Teater M, Smith LE, Rabaia NA, Gurley KE, Guinney J, Busch SE, Shaknovich R, Lobanenkov VV, Liggitt D, Shmulevich I, Melnick A, Filippova GN. Kemp CJ, et al. Among authors: filippova gn. Cell Rep. 2014 May 22;7(4):1020-9. doi: 10.1016/j.celrep.2014.04.004. Epub 2014 May 1. Cell Rep. 2014. PMID: 24794443 Free PMC article.

2

Loss of maternal CTCF is associated with peri-implantation lethality of Ctcf null embryos.

Moore JM, Rabaia NA, Smith LE, Fagerlie S, Gurley K, Loukinov D, Disteche CM, Collins SJ, Kemp CJ, Lobanenkov VV, Filippova GN. Moore JM, et al. Among authors: filippova gn. PLoS One. 2012;7(4):e34915. doi: 10.1371/journal.pone.0034915. Epub 2012 Apr 20. PLoS One. 2012. PMID: 22532833 Free PMC article.

3

Boundaries between chromosomal domains of X inactivation and escape bind CTCF and lack CpG methylation during early development.

Filippova GN, Cheng MK, Moore JM, Truong JP, Hu YJ, Nguyen DK, Tsuchiya KD, Disteche CM. Filippova GN, et al. Dev Cell. 2005 Jan;8(1):31-42. doi: 10.1016/j.devcel.2004.10.018. Dev Cell. 2005. PMID: 15669143 Free article.

4

CTCF is conserved from Drosophila to humans and confers enhancer blocking of the Fab-8 insulator.

Moon H, Filippova G, Loukinov D, Pugacheva E, Chen Q, Smith ST, Munhall A, Grewe B, Bartkuhn M, Arnold R, Burke LJ, Renkawitz-Pohl R, Ohlsson R, Zhou J, Renkawitz R, Lobanenkov V. Moon H, et al. EMBO Rep. 2005 Feb;6(2):165-70. doi: 10.1038/sj.embor.7400334. EMBO Rep. 2005. PMID: 15678159 Free PMC article.

5

Tumor-associated zinc finger mutations in the CTCF transcription factor selectively alter tts DNA-binding specificity.

Filippova GN, Qi CF, Ulmer JE, Moore JM, Ward MD, Hu YJ, Loukinov DI, Pugacheva EM, Klenova EM, Grundy PE, Feinberg AP, Cleton-Jansen AM, Moerland EW, Cornelisse CJ, Suzuki H, Komiya A, Lindblom A, Dorion-Bonnet F, Neiman PE, Morse HC 3rd, Collins SJ, Lobanenkov VV. Filippova GN, et al. Cancer Res. 2002 Jan 1;62(1):48-52. Cancer Res. 2002. PMID: 11782357

6

An antisense transcript spanning the CGG repeat region of FMR1 is upregulated in premutation carriers but silenced in full mutation individuals.

Ladd PD, Smith LE, Rabaia NA, Moore JM, Georges SA, Hansen RS, Hagerman RJ, Tassone F, Tapscott SJ, Filippova GN. Ladd PD, et al. Among authors: filippova gn. Hum Mol Genet. 2007 Dec 15;16(24):3174-87. doi: 10.1093/hmg/ddm293. Epub 2007 Oct 6. Hum Mol Genet. 2007. PMID: 17921506

7

The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation.

Yang F, Deng X, Ma W, Berletch JB, Rabaia N, Wei G, Moore JM, Filippova GN, Xu J, Liu Y, Noble WS, Shendure J, Disteche CM. Yang F, et al. Among authors: filippova gn. Genome Biol. 2015 Mar 12;16(1):52. doi: 10.1186/s13059-015-0618-0. Genome Biol. 2015. PMID: 25887447 Free PMC article.

8

CTCF Expression is Essential for Somatic Cell Viability and Protection Against Cancer.

Bailey CG, Metierre C, Feng Y, Baidya K, Filippova GN, Loukinov DI, Lobanenkov VV, Semaan C, Rasko JE. Bailey CG, et al. Among authors: filippova gn. Int J Mol Sci. 2018 Nov 30;19(12):3832. doi: 10.3390/ijms19123832. Int J Mol Sci. 2018. PMID: 30513694 Free PMC article.

9

A widely expressed transcription factor with multiple DNA sequence specificity, CTCF, is localized at chromosome segment 16q22.1 within one of the smallest regions of overlap for common deletions in breast and prostate cancers.

Filippova GN, Lindblom A, Meincke LJ, Klenova EM, Neiman PE, Collins SJ, Doggett NA, Lobanenkov VV. Filippova GN, et al. Genes Chromosomes Cancer. 1998 May;22(1):26-36. Genes Chromosomes Cancer. 1998. PMID: 9591631

10

Negative transcriptional regulation mediated by thyroid hormone response element 144 requires binding of the multivalent factor CTCF to a novel target DNA sequence.

Awad TA, Bigler J, Ulmer JE, Hu YJ, Moore JM, Lutz M, Neiman PE, Collins SJ, Renkawitz R, Lobanenkov VV, Filippova GN. Awad TA, et al. Among authors: filippova gn. J Biol Chem. 1999 Sep 17;274(38):27092-8. doi: 10.1074/jbc.274.38.27092. J Biol Chem. 1999. PMID: 10480923 Free article.

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