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CD39 limits P2X7 receptor inflammatory signaling and attenuates sepsis-induced liver injury.
Savio LEB, de Andrade Mello P, Figliuolo VR, de Avelar Almeida TF, Santana PT, Oliveira SDS, Silva CLM, Feldbrügge L, Csizmadia E, Minshall RD, Longhi MS, Wu Y, Robson SC, Coutinho-Silva R. Savio LEB, et al. Among authors: figliuolo vr. J Hepatol. 2017 Oct;67(4):716-726. doi: 10.1016/j.jhep.2017.05.021. Epub 2017 May 26. J Hepatol. 2017. PMID: 28554875 Free PMC article.
Infection with Leishmania amazonensis upregulates purinergic receptor expression and induces host-cell susceptibility to UTP-mediated apoptosis.
Marques-da-Silva C, Chaves MM, Chaves SP, Figliuolo VR, Meyer-Fernandes JR, Corte-Real S, Lameu C, Ulrich H, Ojcius DM, Rossi-Bergmann B, Coutinho-Silva R. Marques-da-Silva C, et al. Among authors: figliuolo vr. Cell Microbiol. 2011 Sep;13(9):1410-28. doi: 10.1111/j.1462-5822.2011.01630.x. Epub 2011 Jul 11. Cell Microbiol. 2011. PMID: 21740498
Extracellular ATP induces cell death in human intestinal epithelial cells.
Souza CO, Santoro GF, Figliuolo VR, Nanini HF, de Souza HS, Castelo-Branco MT, Abalo AA, Paiva MM, Coutinho CM, Coutinho-Silva R. Souza CO, et al. Among authors: figliuolo vr. Biochim Biophys Acta. 2012 Dec;1820(12):1867-78. doi: 10.1016/j.bbagen.2012.08.013. Epub 2012 Aug 19. Biochim Biophys Acta. 2012. PMID: 22951220
P2X7 receptor promotes intestinal inflammation in chemically induced colitis and triggers death of mucosal regulatory T cells.
Figliuolo VR, Savio LEB, Safya H, Nanini H, Bernardazzi C, Abalo A, de Souza HSP, Kanellopoulos J, Bobé P, Coutinho CMLM, Coutinho-Silva R. Figliuolo VR, et al. Biochim Biophys Acta Mol Basis Dis. 2017 Jun;1863(6):1183-1194. doi: 10.1016/j.bbadis.2017.03.004. Epub 2017 Mar 7. Biochim Biophys Acta Mol Basis Dis. 2017. PMID: 28286160 Free article.
Intralesional uridine-5'-triphosphate (UTP) treatment induced resistance to Leishmania amazonensis infection by boosting Th1 immune responses and reactive oxygen species production.
Marques-da-Silva C, Chaves MM, Thorstenberg ML, Figliuolo VR, Vieira FS, Chaves SP, Meyer-Fernandes JR, Rossi-Bergmann B, Savio LEB, Coutinho-Silva R. Marques-da-Silva C, et al. Among authors: figliuolo vr. Purinergic Signal. 2018 Jun;14(2):201-211. doi: 10.1007/s11302-018-9606-7. Epub 2018 Apr 21. Purinergic Signal. 2018. PMID: 29680937 Free PMC article.
16 results