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Multiscale Model of Antiviral Timing, Potency, and Heterogeneity Effects on an Epithelial Tissue Patch Infected by SARS-CoV-2.
Viruses. 2022 Mar 14;14(3):605. doi: 10.3390/v14030605.
Viruses. 2022.
PMID: 35337012
Free PMC article.
A modular framework for multiscale, multicellular, spatiotemporal modeling of acute primary viral infection and immune response in epithelial tissues and its application to drug therapy timing and effectiveness.
Sego TJ, Aponte-Serrano JO, Ferrari Gianlupi J, Heaps SR, Breithaupt K, Brusch L, Crawshaw J, Osborne JM, Quardokus EM, Plemper RK, Glazier JA.
Sego TJ, et al. Among authors: ferrari gianlupi j.
PLoS Comput Biol. 2020 Dec 21;16(12):e1008451. doi: 10.1371/journal.pcbi.1008451. eCollection 2020 Dec.
PLoS Comput Biol. 2020.
PMID: 33347439
Free PMC article.
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