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Histone variant H2A.Z deposition and acetylation directs the canonical Notch signaling response.
Giaimo BD, Ferrante F, Vallejo DM, Hein K, Gutierrez-Perez I, Nist A, Stiewe T, Mittler G, Herold S, Zimmermann T, Bartkuhn M, Schwarz P, Oswald F, Dominguez M, Borggrefe T. Giaimo BD, et al. Among authors: ferrante f. Nucleic Acids Res. 2018 Sep 19;46(16):8197-8215. doi: 10.1093/nar/gky551. Nucleic Acids Res. 2018. PMID: 29986055 Free PMC article.
A phospho-dependent mechanism involving NCoR and KMT2D controls a permissive chromatin state at Notch target genes.
Oswald F, Rodriguez P, Giaimo BD, Antonello ZA, Mira L, Mittler G, Thiel VN, Collins KJ, Tabaja N, Cizelsky W, Rothe M, Kühl SJ, Kühl M, Ferrante F, Hein K, Kovall RA, Dominguez M, Borggrefe T. Oswald F, et al. Among authors: ferrante f. Nucleic Acids Res. 2016 Jun 2;44(10):4703-20. doi: 10.1093/nar/gkw105. Epub 2016 Feb 23. Nucleic Acids Res. 2016. PMID: 26912830 Free PMC article.
Dll4 and Notch signalling couples sprouting angiogenesis and artery formation.
Pitulescu ME, Schmidt I, Giaimo BD, Antoine T, Berkenfeld F, Ferrante F, Park H, Ehling M, Biljes D, Rocha SF, Langen UH, Stehling M, Nagasawa T, Ferrara N, Borggrefe T, Adams RH. Pitulescu ME, et al. Among authors: ferrante f. Nat Cell Biol. 2017 Aug;19(8):915-927. doi: 10.1038/ncb3555. Epub 2017 Jul 17. Nat Cell Biol. 2017. PMID: 28714968
RBPJ/CBF1 interacts with L3MBTL3/MBT1 to promote repression of Notch signaling via histone demethylase KDM1A/LSD1.
Xu T, Park SS, Giaimo BD, Hall D, Ferrante F, Ho DM, Hori K, Anhezini L, Ertl I, Bartkuhn M, Zhang H, Milon E, Ha K, Conlon KP, Kuick R, Govindarajoo B, Zhang Y, Sun Y, Dou Y, Basrur V, Elenitoba-Johnson KS, Nesvizhskii AI, Ceron J, Lee CY, Borggrefe T, Kovall RA, Rual JF. Xu T, et al. Among authors: ferrante f. EMBO J. 2017 Nov 2;36(21):3232-3249. doi: 10.15252/embj.201796525. Epub 2017 Oct 13. EMBO J. 2017. PMID: 29030483 Free PMC article.
The histone variant H2A.Z in gene regulation.
Giaimo BD, Ferrante F, Herchenröther A, Hake SB, Borggrefe T. Giaimo BD, et al. Among authors: ferrante f. Epigenetics Chromatin. 2019 Jun 14;12(1):37. doi: 10.1186/s13072-019-0274-9. Epigenetics Chromatin. 2019. PMID: 31200754 Free PMC article. Review.
Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.
Diéguez-Hurtado R, Kato K, Giaimo BD, Nieminen-Kelhä M, Arf H, Ferrante F, Bartkuhn M, Zimmermann T, Bixel MG, Eilken HM, Adams S, Borggrefe T, Vajkoczy P, Adams RH. Diéguez-Hurtado R, et al. Among authors: ferrante f. Nat Commun. 2019 Jun 27;10(1):2817. doi: 10.1038/s41467-019-10643-w. Nat Commun. 2019. PMID: 31249304 Free PMC article.
HDAC3 functions as a positive regulator in Notch signal transduction.
Ferrante F, Giaimo BD, Bartkuhn M, Zimmermann T, Close V, Mertens D, Nist A, Stiewe T, Meier-Soelch J, Kracht M, Just S, Klöble P, Oswald F, Borggrefe T. Ferrante F, et al. Nucleic Acids Res. 2020 Apr 17;48(7):3496-3512. doi: 10.1093/nar/gkaa088. Nucleic Acids Res. 2020. PMID: 32107550 Free PMC article.
284 results