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Targeting the tubulin C-terminal tail by charged small molecules.
Li S, Mori M, Yang M, Elfazazi S, Hortigüela R, Chan P, Feng X, Risinger A, Yang Z, Oliva MÁ, Fernando Díaz J, Fang WS. Li S, et al. Among authors: fernando diaz j. Org Biomol Chem. 2022 Dec 21;21(1):153-162. doi: 10.1039/d2ob01910h. Org Biomol Chem. 2022. PMID: 36472095
Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties.
Gilson P, Josa-Prado F, Beauvineau C, Naud-Martin D, Vanwonterghem L, Mahuteau-Betzer F, Moreno A, Falson P, Lafanechère L, Frachet V, Coll JL, Fernando Díaz J, Hurbin A, Busser B. Gilson P, et al. Among authors: fernando diaz j. Sci Rep. 2017 Aug 31;7(1):10209. doi: 10.1038/s41598-017-09491-9. Sci Rep. 2017. PMID: 28860487 Free PMC article.
Structural Basis of Microtubule Stabilization by Discodermolide.
Prota AE, Bargsten K, Redondo-Horcajo M, Smith AB 3rd, Yang CH, McDaid HM, Paterson I, Horwitz SB, Fernando Díaz J, Steinmetz MO. Prota AE, et al. Among authors: fernando diaz j. Chembiochem. 2017 May 18;18(10):905-909. doi: 10.1002/cbic.201600696. Epub 2017 Mar 27. Chembiochem. 2017. PMID: 28207984 Free PMC article.
Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents.
Milelli A, Tumiatti V, Micco M, Rosini M, Zuccari G, Raffaghello L, Bianchi G, Pistoia V, Fernando Díaz J, Pera B, Trigili C, Barasoain I, Musetti C, Toniolo M, Sissi C, Alcaro S, Moraca F, Zini M, Stefanelli C, Minarini A. Milelli A, et al. Among authors: fernando diaz j. Eur J Med Chem. 2012 Nov;57:417-28. doi: 10.1016/j.ejmech.2012.06.045. Epub 2012 Jul 4. Eur J Med Chem. 2012. PMID: 22819507