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Synthesis and Structure-Activity Relationship Studies of C(13)-Desmethylene-(-)-Zampanolide Analogs.
Chemistry. 2023 Jun 27;29(36):e202300703. doi: 10.1002/chem.202300703. Epub 2023 May 22.
Chemistry. 2023.
PMID: 37057902
Targeting the tubulin C-terminal tail by charged small molecules.
Li S, Mori M, Yang M, Elfazazi S, Hortigüela R, Chan P, Feng X, Risinger A, Yang Z, Oliva MÁ, Fernando Díaz J, Fang WS.
Li S, et al. Among authors: fernando diaz j.
Org Biomol Chem. 2022 Dec 21;21(1):153-162. doi: 10.1039/d2ob01910h.
Org Biomol Chem. 2022.
PMID: 36472095
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Design, Synthesis, and in vitro Evaluation of Tubulin-Targeting Dibenzothiazines with Antiproliferative Activity as a Novel Heterocycle Building Block.
Guerra WD, Lucena-Agell D, Hortigüela R, Rossi RA, Fernando Díaz J, Padrón JM, Barolo SM.
Guerra WD, et al. Among authors: fernando diaz j.
ChemMedChem. 2021 Oct 6;16(19):3003-3016. doi: 10.1002/cmdc.202100383. Epub 2021 Jul 29.
ChemMedChem. 2021.
PMID: 34231318
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Identification of pyrrolopyrimidine derivative PP-13 as a novel microtubule-destabilizing agent with promising anticancer properties.
Gilson P, Josa-Prado F, Beauvineau C, Naud-Martin D, Vanwonterghem L, Mahuteau-Betzer F, Moreno A, Falson P, Lafanechère L, Frachet V, Coll JL, Fernando Díaz J, Hurbin A, Busser B.
Gilson P, et al. Among authors: fernando diaz j.
Sci Rep. 2017 Aug 31;7(1):10209. doi: 10.1038/s41598-017-09491-9.
Sci Rep. 2017.
PMID: 28860487
Free PMC article.
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Structural Basis of Microtubule Stabilization by Discodermolide.
Prota AE, Bargsten K, Redondo-Horcajo M, Smith AB 3rd, Yang CH, McDaid HM, Paterson I, Horwitz SB, Fernando Díaz J, Steinmetz MO.
Prota AE, et al. Among authors: fernando diaz j.
Chembiochem. 2017 May 18;18(10):905-909. doi: 10.1002/cbic.201600696. Epub 2017 Mar 27.
Chembiochem. 2017.
PMID: 28207984
Free PMC article.
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Structure-activity relationships of novel substituted naphthalene diimides as anticancer agents.
Milelli A, Tumiatti V, Micco M, Rosini M, Zuccari G, Raffaghello L, Bianchi G, Pistoia V, Fernando Díaz J, Pera B, Trigili C, Barasoain I, Musetti C, Toniolo M, Sissi C, Alcaro S, Moraca F, Zini M, Stefanelli C, Minarini A.
Milelli A, et al. Among authors: fernando diaz j.
Eur J Med Chem. 2012 Nov;57:417-28. doi: 10.1016/j.ejmech.2012.06.045. Epub 2012 Jul 4.
Eur J Med Chem. 2012.
PMID: 22819507
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Comparative binding energy (COMBINE) analysis supports a proposal for the binding mode of epothilones to β-tubulin.
Coderch C, Klett J, Morreale A, Fernando Díaz J, Gago F.
Coderch C, et al. Among authors: fernando diaz j.
ChemMedChem. 2012 May;7(5):836-43. doi: 10.1002/cmdc.201200065. Epub 2012 Mar 16.
ChemMedChem. 2012.
PMID: 22431398
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Kinetics of dissociation of the tubulin-colchicine complex. Complete reaction scheme and comparison to thermodynamic measurements.
Fernando Díaz J, Andreu JM.
Fernando Díaz J, et al.
J Biol Chem. 1991 Feb 15;266(5):2890-6.
J Biol Chem. 1991.
PMID: 1993663
Free article.
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