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Ribosomal protein RPL22/eL22 regulates the cell cycle by acting as an inhibitor of the CDK4-cyclin D complex.
Del Toro N, Fernandez-Ruiz A, Mignacca L, Kalegari P, Rowell MC, Igelmann S, Saint-Germain E, Benfdil M, Lopes-Paciencia S, Brakier-Gingras L, Bourdeau V, Ferbeyre G, Lessard F. Del Toro N, et al. Among authors: fernandez ruiz a. Cell Cycle. 2019 Mar-Apr;18(6-7):759-770. doi: 10.1080/15384101.2019.1593708. Epub 2019 Mar 28. Cell Cycle. 2019. PMID: 30874462 Free PMC article.
A hydride transfer complex reprograms NAD metabolism and bypasses senescence.
Igelmann S, Lessard F, Uchenunu O, Bouchard J, Fernandez-Ruiz A, Rowell MC, Lopes-Paciencia S, Papadopoli D, Fouillen A, Ponce KJ, Huot G, Mignacca L, Benfdil M, Kalegari P, Wahba HM, Pencik J, Vuong N, Quenneville J, Guillon J, Bourdeau V, Hulea L, Gagnon E, Kenner L, Moriggl R, Nanci A, Pollak MN, Omichinski JG, Topisirovic I, Ferbeyre G. Igelmann S, et al. Among authors: fernandez ruiz a. Mol Cell. 2021 Sep 16;81(18):3848-3865.e19. doi: 10.1016/j.molcel.2021.08.028. Mol Cell. 2021. PMID: 34547241 Free article.
Targeting ribosome biogenesis reinforces ERK-dependent senescence in pancreatic cancer.
Rowell MC, Deschênes-Simard X, Lopes-Paciencia S, Le Calvé B, Kalegari P, Mignacca L, Fernandez-Ruiz A, Guillon J, Lessard F, Bourdeau V, Igelmann S, Duman AM, Stanom Y, Kottakis F, Deshpande V, Krizhanovsky V, Bardeesy N, Ferbeyre G. Rowell MC, et al. Among authors: fernandez ruiz a. Cell Cycle. 2023 Oct;22(19):2172-2193. doi: 10.1080/15384101.2023.2278945. Epub 2023 Dec 5. Cell Cycle. 2023. PMID: 37942963
Interictal epileptiform discharges affect memory in an Alzheimer's disease mouse model.
Soula M, Maslarova A, Harvey RE, Valero M, Brandner S, Hamer H, Fernández-Ruiz A, Buzsáki G. Soula M, et al. Among authors: fernandez ruiz a. Proc Natl Acad Sci U S A. 2023 Aug 22;120(34):e2302676120. doi: 10.1073/pnas.2302676120. Epub 2023 Aug 17. Proc Natl Acad Sci U S A. 2023. PMID: 37590406 Free PMC article.
63 results