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Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring.
Sun J, Esplugues E, Bort A, Cardelo MP, Ruz-Maldonado I, Fernández-Tussy P, Wong C, Wang H, Ojima I, Kaczocha M, Perry R, Suárez Y, Fernández-Hernando C. Sun J, et al. Among authors: fernandez tussy p. Nat Metab. 2024 Apr;6(4):741-763. doi: 10.1038/s42255-024-01019-6. Epub 2024 Apr 25. Nat Metab. 2024. PMID: 38664583
microRNA-33 controls hunger signaling in hypothalamic AgRP neurons.
Price NL, Fernández-Tussy P, Varela L, Cardelo MP, Shanabrough M, Aryal B, de Cabo R, Suárez Y, Horvath TL, Fernández-Hernando C. Price NL, et al. Among authors: fernandez tussy p. Nat Commun. 2024 Mar 8;15(1):2131. doi: 10.1038/s41467-024-46427-0. Nat Commun. 2024. PMID: 38459068 Free PMC article.
DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time.
Relovska S, Wang H, Zhang X, Fernández-Tussy P, Jeong KJ, Choi J, Suárez Y, McDonald JG, Fernández-Hernando C, Chung JJ. Relovska S, et al. Among authors: fernandez tussy p. bioRxiv [Preprint]. 2024 Feb 11:2023.12.21.572851. doi: 10.1101/2023.12.21.572851. bioRxiv. 2024. PMID: 38187697 Free PMC article. Preprint.
Hepatocyte-specific miR-33 deletion attenuates NAFLD-NASH-HCC progression.
Fernández-Tussy P, Sun J, Cardelo MP, Price NL, Goedeke L, Xirouchaki CE, Yang X, Pastor-Rojo O, Bennett AM, Tiganis T, Suárez Y, Fernández-Hernando C. Fernández-Tussy P, et al. bioRxiv [Preprint]. 2023 Jan 20:2023.01.18.523503. doi: 10.1101/2023.01.18.523503. bioRxiv. 2023. PMID: 36711578 Free PMC article. Preprint.
Fibronectin-Integrin α5 Signaling in Vascular Complications of Type 1 Diabetes.
Chen M, Hu R, Cavinato C, Zhuang ZW, Zhang J, Yun S, Fernandez Tussy P, Singh A, Murtada SI, Tanaka K, Liu M, Fernández-Hernando C, Humphrey JD, Schwartz MA. Chen M, et al. Among authors: fernandez tussy p. Diabetes. 2022 Sep 1;71(9):2020-2033. doi: 10.2337/db21-0958. Diabetes. 2022. PMID: 35771994 Free PMC article.
Methionine Cycle Rewiring by Targeting miR-873-5p Modulates Ammonia Metabolism to Protect the Liver from Acetaminophen.
Rodríguez-Agudo R, Goikoetxea-Usandizaga N, Serrano-Maciá M, Fernández-Tussy P, Fernández-Ramos D, Lachiondo-Ortega S, González-Recio I, Gil-Pitarch C, Mercado-Gómez M, Morán L, Bizkarguenaga M, Lopitz-Otsoa F, Petrov P, Bravo M, Van Liempd SM, Falcon-Perez JM, Zabala-Letona A, Carracedo A, Castell JV, Jover R, Martínez-Cruz LA, Delgado TC, Cubero FJ, Lucena MI, Andrade RJ, Mabe J, Simón J, Martínez-Chantar ML. Rodríguez-Agudo R, et al. Among authors: fernandez tussy p. Antioxidants (Basel). 2022 Apr 30;11(5):897. doi: 10.3390/antiox11050897. Antioxidants (Basel). 2022. PMID: 35624761 Free PMC article.
Anti-miR-518d-5p overcomes liver tumor cell death resistance through mitochondrial activity.
Fernández-Tussy P, Rodríguez-Agudo R, Fernández-Ramos D, Barbier-Torres L, Zubiete-Franco I, Davalillo SL, Herraez E, Goikoetxea-Usandizaga N, Lachiondo-Ortega S, Simón J, Lopitz-Otsoa F, Juan VG, McCain MV, Perugorria MJ, Mabe J, Navasa N, Rodrigues CMP, Fabregat I, Boix L, Sapena V, Anguita J, Lu SC, Mato JM, Banales JM, Villa E, Reeves HL, Bruix J, Reig M, Marin JJG, Delgado TC, Martínez-Chantar ML. Fernández-Tussy P, et al. Cell Death Dis. 2021 May 28;12(6):555. doi: 10.1038/s41419-021-03827-0. Cell Death Dis. 2021. PMID: 34050139 Free PMC article.
Boosting mitochondria activity by silencing MCJ overcomes cholestasis-induced liver injury.
Iruzubieta P, Goikoetxea-Usandizaga N, Barbier-Torres L, Serrano-Maciá M, Fernández-Ramos D, Fernández-Tussy P, Gutiérrez-de-Juan V, Lachiondo-Ortega S, Simon J, Bravo M, Lopitz-Otsoa F, Robles M, Ferre-Aracil C, Varela-Rey M, Elguezabal N, Calleja JL, Lu SC, Milkiewicz M, Milkiewicz P, Anguita J, Monte MJ, Marin JJG, López-Hoyos M, Delgado TC, Rincón M, Crespo J, Martínez-Chantar ML. Iruzubieta P, et al. Among authors: fernandez tussy p. JHEP Rep. 2021 Mar 18;3(3):100276. doi: 10.1016/j.jhepr.2021.100276. eCollection 2021 Jun. JHEP Rep. 2021. PMID: 33997750 Free PMC article.
24 results