Fernández-Murga ML - Search Results

1

Advances in drug-induced cholestasis: Clinical perspectives, potential mechanisms and in vitro systems.

Fernández-Murga ML, Petrov PD, Conde I, Castell JV, Goméz-Lechón MJ, Jover R. Fernández-Murga ML, et al. Food Chem Toxicol. 2018 Oct;120:196-212. doi: 10.1016/j.fct.2018.07.017. Epub 2018 Jul 7. Food Chem Toxicol. 2018. PMID: 29990576 Review.

2

Predicting drug-induced cholestasis: preclinical models.

Petrov PD, Fernández-Murga ML, López-Riera M, Goméz-Lechón MJ, Castell JV, Jover R. Petrov PD, et al. Among authors: fernandez murga ml. Expert Opin Drug Metab Toxicol. 2018 Jul;14(7):721-738. doi: 10.1080/17425255.2018.1487399. Epub 2018 Jun 20. Expert Opin Drug Metab Toxicol. 2018. PMID: 29888962 Review.

3

Functional dissection of N-acetylglutamate synthase (ArgA) of Pseudomonas aeruginosa and restoration of its ancestral N-acetylglutamate kinase activity.

Sancho-Vaello E, Fernández-Murga ML, Rubio V. Sancho-Vaello E, et al. J Bacteriol. 2012 Jun;194(11):2791-801. doi: 10.1128/JB.00125-12. Epub 2012 Mar 23. J Bacteriol. 2012. PMID: 22447897 Free PMC article.

4

Towards structural understanding of feedback control of arginine biosynthesis: cloning and expression of the gene for the arginine-inhibited N-acetyl-L-glutamate kinase from Pseudomonas aeruginosa, purification and crystallization of the recombinant enzyme and preliminary X-ray studies.

Fernández-Murga ML, Ramón-Maiques S, Gil-Ortiz F, Fita I, Rubio V. Fernández-Murga ML, et al. Acta Crystallogr D Biol Crystallogr. 2002 Jun;58(Pt 6 Pt 2):1045-7. doi: 10.1107/s0907444902005243. Epub 2002 May 29. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12037312

5

Arginine biosynthesis in Thermotoga maritima: characterization of the arginine-sensitive N-acetyl-L-glutamate kinase.

Fernández-Murga ML, Gil-Ortiz F, Llácer JL, Rubio V. Fernández-Murga ML, et al. J Bacteriol. 2004 Sep;186(18):6142-9. doi: 10.1128/JB.186.18.6142-6149.2004. J Bacteriol. 2004. PMID: 15342584 Free PMC article.

6

Structural bases of feed-back control of arginine biosynthesis, revealed by the structures of two hexameric N-acetylglutamate kinases, from Thermotoga maritima and Pseudomonas aeruginosa.

Ramón-Maiques S, Fernández-Murga ML, Gil-Ortiz F, Vagin A, Fita I, Rubio V. Ramón-Maiques S, et al. J Mol Biol. 2006 Feb 24;356(3):695-713. doi: 10.1016/j.jmb.2005.11.079. Epub 2005 Dec 12. J Mol Biol. 2006. PMID: 16376937

7

Basis of arginine sensitivity of microbial N-acetyl-L-glutamate kinases: mutagenesis and protein engineering study with the Pseudomonas aeruginosa and Escherichia coli enzymes.

Fernández-Murga ML, Rubio V. Fernández-Murga ML, et al. J Bacteriol. 2008 Apr;190(8):3018-25. doi: 10.1128/JB.01831-07. Epub 2008 Feb 8. J Bacteriol. 2008. PMID: 18263723 Free PMC article.

8

Site-directed mutagenesis studies of acetylglutamate synthase delineate the site for the arginine inhibitor.

Sancho-Vaello E, Fernández-Murga ML, Rubio V. Sancho-Vaello E, et al. FEBS Lett. 2008 Apr 2;582(7):1081-6. doi: 10.1016/j.febslet.2008.02.060. Epub 2008 Mar 3. FEBS Lett. 2008. PMID: 18319063 Free article.

9

Two crystal structures of Escherichia coli N-acetyl-L-glutamate kinase demonstrate the cycling between open and closed conformations.

Gil-Ortiz F, Ramón-Maiques S, Fernández-Murga ML, Fita I, Rubio V. Gil-Ortiz F, et al. J Mol Biol. 2010 Jun 11;399(3):476-90. doi: 10.1016/j.jmb.2010.04.025. Epub 2010 Apr 18. J Mol Biol. 2010. PMID: 20403363

10

Use of pure recombinant human enzymes to assess the disease-causing potential of missense mutations in urea cycle disorders, applied to N-acetylglutamate synthase deficiency.

Gougeard N, Sancho-Vaello E, Fernández-Murga ML, Martínez-Sinisterra B, Loukili-Hassani B, Häberle J, Marco-Marín C, Rubio V. Gougeard N, et al. Among authors: fernandez murga ml. J Inherit Metab Dis. 2024 May 13. doi: 10.1002/jimd.12747. Online ahead of print. J Inherit Metab Dis. 2024. PMID: 38740568

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

32 results

Search Page