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Hepatocyte-specific miR-33 deletion attenuates NAFLD-NASH-HCC progression.
Fernández-Tussy P, Sun J, Cardelo MP, Price NL, Goedeke L, Xirouchaki CE, Yang X, Pastor-Rojo O, Bennett AM, Tiganis T, Suárez Y, Fernández-Hernando C. Fernández-Tussy P, et al. bioRxiv [Preprint]. 2023 Jan 20:2023.01.18.523503. doi: 10.1101/2023.01.18.523503. bioRxiv. 2023. PMID: 36711578 Free PMC article. Preprint.
Fatty acid binding protein 5 suppression attenuates obesity-induced hepatocellular carcinoma by promoting ferroptosis and intratumoral immune rewiring.
Sun J, Esplugues E, Bort A, Cardelo MP, Ruz-Maldonado I, Fernández-Tussy P, Wong C, Wang H, Ojima I, Kaczocha M, Perry R, Suárez Y, Fernández-Hernando C. Sun J, et al. Among authors: fernandez hernando c. Nat Metab. 2024 Apr;6(4):741-763. doi: 10.1038/s42255-024-01019-6. Epub 2024 Apr 25. Nat Metab. 2024. PMID: 38664583
microRNA-33 controls hunger signaling in hypothalamic AgRP neurons.
Price NL, Fernández-Tussy P, Varela L, Cardelo MP, Shanabrough M, Aryal B, de Cabo R, Suárez Y, Horvath TL, Fernández-Hernando C. Price NL, et al. Among authors: fernandez hernando c. Nat Commun. 2024 Mar 8;15(1):2131. doi: 10.1038/s41467-024-46427-0. Nat Commun. 2024. PMID: 38459068 Free PMC article.
DHCR24-mediated sterol homeostasis during spermatogenesis is required for sperm mitochondrial sheath formation and impacts male fertility over time.
Relovska S, Wang H, Zhang X, Fernández-Tussy P, Jeong KJ, Choi J, Suárez Y, McDonald JG, Fernández-Hernando C, Chung JJ. Relovska S, et al. Among authors: fernandez hernando c. bioRxiv [Preprint]. 2024 Feb 11:2023.12.21.572851. doi: 10.1101/2023.12.21.572851. bioRxiv. 2024. PMID: 38187697 Free PMC article. Preprint.
Dynamic metabolism of endothelial triglycerides protects against atherosclerosis in mice.
Boutagy NE, Gamez-Mendez A, Fowler JW, Zhang H, Chaube BK, Esplugues E, Kuo A, Lee S, Horikami D, Zhang J, Citrin KM, Singh AK, Coon BG, Lee MY, Suarez Y, Fernandez-Hernando C, Sessa WC. Boutagy NE, et al. Among authors: fernandez hernando c. J Clin Invest. 2024 Jan 4;134(4):e170453. doi: 10.1172/JCI170453. J Clin Invest. 2024. PMID: 38175710 Free PMC article.
Loss of cis-PTase function in the liver promotes a highly penetrant form of fatty liver disease that rapidly transitions to hepatocellular carcinoma.
Singh AK, Chaube B, Citrin KM, Fowler JW, Lee S, Catarino J, Knight J, Lowery S, Shree S, Boutagy N, Ruz-Maldonado I, Harry K, Shanabrough M, Ross TT, Malaker S, Suárez Y, Fernández-Hernando C, Grabinska K, Sessa WC. Singh AK, et al. Among authors: fernandez hernando c. bioRxiv [Preprint]. 2023 Nov 15:2023.11.13.566870. doi: 10.1101/2023.11.13.566870. bioRxiv. 2023. PMID: 38014178 Free PMC article. Preprint.
185 results