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Page 1
A personalized medicine approach identifies enasidenib as an efficient treatment for IDH2 mutant chondrosarcoma.
Rey V, Tornín J, Alba-Linares JJ, Robledo C, Murillo D, Rodríguez A, Gallego B, Huergo C, Viera C, Braña A, Astudillo A, Heymann D, Szuhai K, Bovée JVMG, Fernández AF, Fraga MF, Alonso J, Rodríguez R. Rey V, et al. Among authors: fernandez af. EBioMedicine. 2024 Apr;102:105090. doi: 10.1016/j.ebiom.2024.105090. Epub 2024 Mar 27. EBioMedicine. 2024. PMID: 38547578 Free PMC article.
Is there a preferred platinum and fluoropyrimidine regimen for advanced HER2-negative esophagogastric adenocarcinoma? Insights from 1293 patients in AGAMENON-SEOM registry.
Arias-Martinez A, Martínez de Castro E, Gallego J, Arrazubi V, Custodio A, Fernández Montes A, Diez M, Hernandez R, Limón ML, Cano JM, Vidal-Tocino R, Macias I, Visa L, Martin Richard M, Sauri T, Hierro C, Gil M, Cerda P, Martínez Moreno E, Martínez Lago N, Mérida-García AJ, Gómez González L, García Navalón FJ, Ruiz Martín M, Marín G, López-López F, Ruperez Blanco AB, Fernández AF, Jimenez-Fonseca P, Carmona-Bayonas A, Alvarez-Manceñido F. Arias-Martinez A, et al. Among authors: fernandez af. Clin Transl Oncol. 2024 Feb 15. doi: 10.1007/s12094-024-03388-6. Online ahead of print. Clin Transl Oncol. 2024. PMID: 38361134
A complex interplay between H2A.Z and HP1 isoforms regulates pericentric heterochromatin.
González J, Bosch-Presegué L, Marazuela-Duque A, Guitart-Solanes A, Espinosa-Alcantud M, Fernandez AF, Brown JP, Ausió J, Vazquez BN, Singh PB, Fraga MF, Vaquero A. González J, et al. Among authors: fernandez af. Front Cell Dev Biol. 2023 Nov 9;11:1293122. doi: 10.3389/fcell.2023.1293122. eCollection 2023. Front Cell Dev Biol. 2023. PMID: 38020886 Free PMC article.
CRISPR/dCAS9-mediated DNA demethylation screen identifies functional epigenetic determinants of colorectal cancer.
Tejedor JR, Peñarroya A, Gancedo-Verdejo J, Santamarina-Ojeda P, Pérez RF, López-Tamargo S, Díez-Borge A, Alba-Linares JJ, González-Del-Rey N, Urdinguio RG, Mangas C, Roberti A, López V, Morales-Ruiz T, Ariza RR, Roldán-Arjona T, Meijón M, Valledor L, Cañal MJ, Fernández-Martínez D, Fernández-Hevia M, Jiménez-Fonseca P, García-Flórez LJ, Fernández AF, Fraga MF. Tejedor JR, et al. Among authors: fernandez af. Clin Epigenetics. 2023 Aug 24;15(1):133. doi: 10.1186/s13148-023-01546-1. Clin Epigenetics. 2023. PMID: 37612734 Free PMC article.
Nicotinamide N-methyltransferase (NNMT) regulates the glucocorticoid signaling pathway during the early phase of adipogenesis.
Roberti A, Tejedor JR, Díaz-Moreno I, López V, Santamarina-Ojeda P, Pérez RF, Urdinguio RG, Concellón C, Martínez-Chantar ML, Fernández-Morera JL, Díaz-Quintana A, Del Amo V, Fernández AF, Fraga MF. Roberti A, et al. Among authors: fernandez af. Sci Rep. 2023 May 22;13(1):8293. doi: 10.1038/s41598-023-34916-z. Sci Rep. 2023. PMID: 37217546 Free PMC article.
The TINCR ubiquitin-like microprotein is a tumor suppressor in squamous cell carcinoma.
Morgado-Palacin L, Brown JA, Martinez TF, Garcia-Pedrero JM, Forouhar F, Quinn SA, Reglero C, Vaughan J, Heydary YH, Donaldson C, Rodriguez-Perales S, Allonca E, Granda-Diaz R, Fernandez AF, Fraga MF, Kim AL, Santos-Juanes J, Owens DM, Rodrigo JP, Saghatelian A, Ferrando AA. Morgado-Palacin L, et al. Among authors: fernandez af. Nat Commun. 2023 Mar 10;14(1):1328. doi: 10.1038/s41467-023-36713-8. Nat Commun. 2023. PMID: 36899004 Free PMC article.
Maternal obesity and gestational diabetes reprogram the methylome of offspring beyond birth by inducing epigenetic signatures in metabolic and developmental pathways.
Alba-Linares JJ, Pérez RF, Tejedor JR, Bastante-Rodríguez D, Ponce F, Carbonell NG, Zafra RG, Fernández AF, Fraga MF, Lurbe E. Alba-Linares JJ, et al. Among authors: fernandez af. Cardiovasc Diabetol. 2023 Mar 4;22(1):44. doi: 10.1186/s12933-023-01774-y. Cardiovasc Diabetol. 2023. PMID: 36870961 Free PMC article.
SOCS3 deregulation contributes to aberrant activation of the JAK/STAT pathway in precursor T-cell neoplasms.
Lahera A, López-Nieva P, Alarcón H, Marín-Rubio JL, Cobos-Fernández MÁ, Fernández-Navarro P, Fernández AF, Vela-Martín L, Sastre I, Ruiz-García S, Llamas P, López-Lorenzo JL, Cornago J, Santos J, Fernández-Piqueras J, Villa-Morales M. Lahera A, et al. Among authors: fernandez af. Br J Haematol. 2023 May;201(4):718-724. doi: 10.1111/bjh.18694. Epub 2023 Feb 14. Br J Haematol. 2023. PMID: 36786170
172 results