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Synthesis, Structure-Activity Relationship Study, Bioactivity, and Nephrotoxicity Evaluation of the Proposed Structure of the Cyclic Lipodepsipeptide Brevicidine B.
Palpal-Latoc D, Horsfall AJ, Cameron AJ, Campbell G, Ferguson SA, Cook GM, Sander V, Davidson AJ, Harris PWR, Brimble MA. Palpal-Latoc D, et al. Among authors: ferguson sa. J Nat Prod. 2024 Apr 26;87(4):764-773. doi: 10.1021/acs.jnatprod.3c00876. Epub 2024 Feb 29. J Nat Prod. 2024. PMID: 38423998
"CLipP"ing on lipids to generate antibacterial lipopeptides.
Yim V, Kavianinia I, Knottenbelt MK, Ferguson SA, Cook GM, Swift S, Chakraborty A, Allison JR, Cameron AJ, Harris PWR, Brimble MA. Yim V, et al. Among authors: ferguson sa. Chem Sci. 2020 May 20;11(22):5759-5765. doi: 10.1039/d0sc01814g. Chem Sci. 2020. PMID: 34094080 Free PMC article.
Synthesis, Antibacterial Activity, and Nephrotoxicity of Polymyxin B Analogues Modified at Leu-7, d-Phe-6, and the N-Terminus Enabled by S-Lipidation.
Harris PWR, Siow A, Yang SH, Wadsworth AD, Tan L, Hermant Y, Mao Y, An C, Hanna CC, Cameron AJ, Allison JR, Chakraborty A, Ferguson SA, Mros S, Hards K, Cook GM, Williamson DA, Carter GP, Chan STS, Painter GA, Sander V, Davidson AJ, Brimble MA. Harris PWR, et al. Among authors: ferguson sa. ACS Infect Dis. 2022 Dec 9;8(12):2413-2429. doi: 10.1021/acsinfecdis.1c00347. Epub 2022 Nov 22. ACS Infect Dis. 2022. PMID: 36413173
Substituted sulfonamide bioisosteres of 8-hydroxyquinoline as zinc-dependent antibacterial compounds.
McGowan JE, Harper AD, Davison EK, Jeong JY, Mros S, Harbison-Price N, Van Zuylen EM, Knottenbelt MK, Heikal A, Ferguson SA, McConnell MA, Cook GM, Krittaphol W, Walker GF, Brimble MA, Rennison D. McGowan JE, et al. Among authors: ferguson sa. Bioorg Med Chem Lett. 2020 Jun 1;30(11):127110. doi: 10.1016/j.bmcl.2020.127110. Epub 2020 Mar 16. Bioorg Med Chem Lett. 2020. PMID: 32229060
C-2 derivatized 8-sulfonamidoquinolines as antibacterial compounds.
Davison EK, McGowan JE, Li FF, Harper AD, Jeong JY, Mros S, Harbison-Price N, Van Zuylen EM, Knottenbelt MK, Heikal A, Ferguson SA, McConnell MA, Cook GM, Krittaphol W, Walker GF, Brimble MA, Rennison D. Davison EK, et al. Among authors: ferguson sa. Bioorg Med Chem. 2021 Jan 1;29:115837. doi: 10.1016/j.bmc.2020.115837. Epub 2020 Nov 6. Bioorg Med Chem. 2021. PMID: 33223463
419 results