Ferguson DA - Search Results

1

Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKD.

Lewis JH, Jadoul M, Block GA, Chin MP, Ferguson DA, Goldsberry A, Meyer CJ, O'Grady M, Pergola PE, Reisman SA, Wigley WC, Chertow GM. Lewis JH, et al. Among authors: ferguson da. Clin Transl Sci. 2021 Jan;14(1):299-309. doi: 10.1111/cts.12868. Epub 2020 Sep 3. Clin Transl Sci. 2021. PMID: 32860734 Free PMC article. Clinical Trial.

2

Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKD.

Pergola PE, Krauth M, Huff JW, Ferguson DA, Ruiz S, Meyer CJ, Warnock DG. Pergola PE, et al. Among authors: ferguson da. Am J Nephrol. 2011;33(5):469-76. doi: 10.1159/000327599. Epub 2011 Apr 21. Am J Nephrol. 2011. PMID: 21508635 Free article. Clinical Trial.

3

Bardoxolone methyl (BARD) ameliorates ischemic AKI and increases expression of protective genes Nrf2, PPARγ, and HO-1.

Wu QQ, Wang Y, Senitko M, Meyer C, Wigley WC, Ferguson DA, Grossman E, Chen J, Zhou XJ, Hartono J, Winterberg P, Chen B, Agarwal A, Lu CY. Wu QQ, et al. Among authors: ferguson da. Am J Physiol Renal Physiol. 2011 May;300(5):F1180-92. doi: 10.1152/ajprenal.00353.2010. Epub 2011 Feb 2. Am J Physiol Renal Physiol. 2011. PMID: 21289052 Free PMC article.

4

Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405.

Probst BL, McCauley L, Trevino I, Wigley WC, Ferguson DA. Probst BL, et al. Among authors: ferguson da. PLoS One. 2015 Aug 24;10(8):e0135257. doi: 10.1371/journal.pone.0135257. eCollection 2015. PLoS One. 2015. PMID: 26301506 Free PMC article.

5

The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cells.

Ding Y, Stidham RD, Bumeister R, Trevino I, Winters A, Sprouse M, Ding M, Ferguson DA, Meyer CJ, Wigley WC, Ma R. Ding Y, et al. Among authors: ferguson da. Kidney Int. 2013 May;83(5):845-54. doi: 10.1038/ki.2012.393. Epub 2012 Dec 12. Kidney Int. 2013. PMID: 23235569 Free PMC article.

6

RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory Activity.

Probst BL, Trevino I, McCauley L, Bumeister R, Dulubova I, Wigley WC, Ferguson DA. Probst BL, et al. Among authors: ferguson da. PLoS One. 2015 Apr 21;10(4):e0122942. doi: 10.1371/journal.pone.0122942. eCollection 2015. PLoS One. 2015. PMID: 25897966 Free PMC article.

7

Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitis.

Reisman SA, Ferguson DA, Lee CI, Proksch JW. Reisman SA, et al. Among authors: ferguson da. J Biochem Mol Toxicol. 2020 Sep;34(9):e22526. doi: 10.1002/jbt.22526. Epub 2020 May 14. J Biochem Mol Toxicol. 2020. PMID: 32410268 Free PMC article.

8

A phase I first-in-human trial of bardoxolone methyl in patients with advanced solid tumors and lymphomas.

Hong DS, Kurzrock R, Supko JG, He X, Naing A, Wheler J, Lawrence D, Eder JP, Meyer CJ, Ferguson DA, Mier J, Konopleva M, Konoplev S, Andreeff M, Kufe D, Lazarus H, Shapiro GI, Dezube BJ. Hong DS, et al. Among authors: ferguson da. Clin Cancer Res. 2012 Jun 15;18(12):3396-406. doi: 10.1158/1078-0432.CCR-11-2703. Epub 2012 May 25. Clin Cancer Res. 2012. PMID: 22634319 Free PMC article. Clinical Trial.

9

A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγt.

Jiang X, Dulubova I, Reisman SA, Hotema M, Lee CI, Liu L, McCauley L, Trevino I, Ferguson DA, Eken Y, Wilson AK, Wigley WC, Visnick M. Jiang X, et al. Among authors: ferguson da. Bioorg Med Chem Lett. 2020 Mar 15;30(6):126967. doi: 10.1016/j.bmcl.2020.126967. Epub 2020 Jan 15. Bioorg Med Chem Lett. 2020. PMID: 32005415

10

Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 binding.

Huerta C, Jiang X, Trevino I, Bender CF, Ferguson DA, Probst B, Swinger KK, Stoll VS, Thomas PJ, Dulubova I, Visnick M, Wigley WC. Huerta C, et al. Among authors: ferguson da. Biochim Biophys Acta. 2016 Nov;1860(11 Pt A):2537-2552. doi: 10.1016/j.bbagen.2016.07.026. Epub 2016 Jul 27. Biochim Biophys Acta. 2016. PMID: 27474998

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