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NOX4 Inhibition Potentiates Immunotherapy by Overcoming Cancer-Associated Fibroblast-Mediated CD8 T-cell Exclusion from Tumors.
Ford K, Hanley CJ, Mellone M, Szyndralewiez C, Heitz F, Wiesel P, Wood O, Machado M, Lopez MA, Ganesan AP, Wang C, Chakravarthy A, Fenton TR, King EV, Vijayanand P, Ottensmeier CH, Al-Shamkhani A, Savelyeva N, Thomas GJ. Ford K, et al. Among authors: fenton tr. Cancer Res. 2020 May 1;80(9):1846-1860. doi: 10.1158/0008-5472.CAN-19-3158. Epub 2020 Mar 2. Cancer Res. 2020. PMID: 32122909 Free PMC article.
CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma.
Feber A, Worth DC, Chakravarthy A, de Winter P, Shah K, Arya M, Saqib M, Nigam R, Malone PR, Tan WS, Rodney S, Freeman A, Jameson C, Wilson GA, Powles T, Beck S, Fenton T, Sharp TV, Muneer A, Kelly JD. Feber A, et al. Cancer Res. 2016 Aug 15;76(16):4720-4727. doi: 10.1158/0008-5472.CAN-15-3134. Epub 2016 Jun 20. Cancer Res. 2016. PMID: 27325650 Free PMC article.
Human Papillomavirus Drives Tumor Development Throughout the Head and Neck: Improved Prognosis Is Associated With an Immune Response Largely Restricted to the Oropharynx.
Chakravarthy A, Henderson S, Thirdborough SM, Ottensmeier CH, Su X, Lechner M, Feber A, Thomas GJ, Fenton TR. Chakravarthy A, et al. Among authors: fenton tr. J Clin Oncol. 2016 Dec;34(34):4132-4141. doi: 10.1200/JCO.2016.68.2955. Epub 2016 Oct 31. J Clin Oncol. 2016. PMID: 27863190 Free PMC article.
Pan-cancer deconvolution of tumour composition using DNA methylation.
Chakravarthy A, Furness A, Joshi K, Ghorani E, Ford K, Ward MJ, King EV, Lechner M, Marafioti T, Quezada SA, Thomas GJ, Feber A, Fenton TR. Chakravarthy A, et al. Among authors: fenton tr. Nat Commun. 2018 Aug 13;9(1):3220. doi: 10.1038/s41467-018-05570-1. Nat Commun. 2018. PMID: 30104673 Free PMC article.
Integrated analysis of cervical squamous cell carcinoma cohorts from three continents reveals conserved subtypes of prognostic significance.
Chakravarthy A, Reddin I, Henderson S, Dong C, Kirkwood N, Jeyakumar M, Rodriguez DR, Martinez NG, McDermott J, Su X, Egawa N, Fjeldbo CS, Skingen VE, Lyng H, Halle MK, Krakstad C, Soleiman A, Sprung S, Lechner M, Ellis PJI, Wass M, Michaelis M, Fiegl H, Salvesen H, Thomas GJ, Doorbar J, Chester K, Feber A, Fenton TR. Chakravarthy A, et al. Among authors: fenton tr. Nat Commun. 2022 Oct 7;13(1):5818. doi: 10.1038/s41467-022-33544-x. Nat Commun. 2022. PMID: 36207323 Free PMC article.
Differentiation signals induce APOBEC3A expression via GRHL3 in squamous epithelia and squamous cell carcinoma.
Smith NJ, Reddin I, Policelli P, Oh S, Zainal N, Howes E, Jenkins B, Tracy I, Edmond M, Sharpe B, Amendra D, Zheng K, Egawa N, Doorbar J, Rao A, Mahadevan S, Carpenter MA, Harris RS, Ali S, Hanley C, Buisson R, King E, Thomas GJ, Fenton TR. Smith NJ, et al. Among authors: fenton tr. Res Sq [Preprint]. 2024 Mar 4:rs.3.rs-3997426. doi: 10.21203/rs.3.rs-3997426/v1. Res Sq. 2024. PMID: 38496447 Free PMC article. Preprint.
Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma.
Lechner M, Fenton T, West J, Wilson G, Feber A, Henderson S, Thirlwell C, Dibra HK, Jay A, Butcher L, Chakravarthy AR, Gratrix F, Patel N, Vaz F, O'Flynn P, Kalavrezos N, Teschendorff AE, Boshoff C, Beck S. Lechner M, et al. Genome Med. 2013 Feb 5;5(2):15. doi: 10.1186/gm419. eCollection 2013. Genome Med. 2013. PMID: 23419152 Free PMC article.
182 results