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Utilization of microbial iron assimilation processes for the development of new antibiotics and inspiration for the design of new anticancer agents.
Miller MJ, Zhu H, Xu Y, Wu C, Walz AJ, Vergne A, Roosenberg JM, Moraski G, Minnick AA, McKee-Dolence J, Hu J, Fennell K, Kurt Dolence E, Dong L, Franzblau S, Malouin F, Möllmann U. Miller MJ, et al. Among authors: fennell k. Biometals. 2009 Feb;22(1):61-75. doi: 10.1007/s10534-008-9185-0. Epub 2009 Jan 7. Biometals. 2009. PMID: 19130268 Free PMC article. Review.
An inverse agonist of orphan receptor GPR61 acts by a G protein-competitive allosteric mechanism.
Lees JA, Dias JM, Rajamohan F, Fortin JP, O'Connor R, Kong JX, Hughes EAG, Fisher EL, Tuttle JB, Lovett G, Kormos BL, Unwalla RJ, Zhang L, Dechert Schmitt AM, Zhou D, Moran M, Stevens KA, Fennell KF, Varghese AE, Maxwell A, Cote EE, Zhang Y, Han S. Lees JA, et al. Among authors: fennell kf. Nat Commun. 2023 Sep 23;14(1):5938. doi: 10.1038/s41467-023-41646-3. Nat Commun. 2023. PMID: 37741852 Free PMC article.
Sex chromosome and gonadal hormone contributions to binge-like and aversion-resistant ethanol drinking behaviors in Four Core Genotypes mice.
Sneddon EA, Masters BM, Ream KD, Fennell KA, DeMedio JN, Cash MM, Hollingsworth BP, Pandrangi S, Thach CM, Shi H, Radke AK. Sneddon EA, et al. Among authors: fennell ka. Front Psychiatry. 2023 Mar 7;14:1098387. doi: 10.3389/fpsyt.2023.1098387. eCollection 2023. Front Psychiatry. 2023. PMID: 36960454 Free PMC article.
Discovery of High-Affinity Small-Molecule Binders of the Epigenetic Reader YEATS4.
Londregan AT, Aitmakhanova K, Bennett J, Byrnes LJ, Canterbury DP, Cheng X, Christott T, Clemens J, Coffey SB, Dias JM, Dowling MS, Farnie G, Fedorov O, Fennell KF, Gamble V, Gileadi C, Giroud C, Harris MR, Hollingshead BD, Huber K, Korczynska M, Lapham K, Loria PM, Narayanan A, Owen DR, Raux B, Sahasrabudhe PV, Ruggeri RB, Sáez LD, Stock IA, Thuma BA, Tsai A, Varghese AE. Londregan AT, et al. Among authors: fennell kf. J Med Chem. 2023 Jan 12;66(1):460-472. doi: 10.1021/acs.jmedchem.2c01421. Epub 2022 Dec 23. J Med Chem. 2023. PMID: 36562986
66 results