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Perspective on the current state of the LRRK2 field.
Taymans JM, Fell M, Greenamyre T, Hirst WD, Mamais A, Padmanabhan S, Peter I, Rideout H, Thaler A. Taymans JM, et al. Among authors: fell m. NPJ Parkinsons Dis. 2023 Jul 1;9(1):104. doi: 10.1038/s41531-023-00544-7. NPJ Parkinsons Dis. 2023. PMID: 37393318 Free PMC article. Review.
Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson's Disease.
Kattar SD, Gulati A, Margrey KA, Keylor MH, Ardolino M, Yan X, Johnson R, Palte RL, McMinn SE, Nogle L, Su J, Xiao D, Piesvaux J, Lee S, Hegde LG, Woodhouse JD, Faltus R, Moy LY, Xiong T, Ciaccio PJ, Pearson K, Patel M, Otte KM, Leyns CEG, Kennedy ME, Bennett DJ, DiMauro EF, Fell MJ, Fuller PH. Kattar SD, et al. Among authors: fell mj. J Med Chem. 2023 Nov 9;66(21):14912-14927. doi: 10.1021/acs.jmedchem.3c01486. Epub 2023 Oct 20. J Med Chem. 2023. PMID: 37861679
Effects of LRRK2 Inhibitors in Nonhuman Primates.
Miller GK, Kuruvilla S, Jacob B, LaFranco-Scheuch L, Bakthavatchalu V, Flor J, Flor K, Ziegler J, Reichard C, Manfre P, Firner S, McNutt T, Quay D, Bellum S, Doto G, Ciaccio PJ, Pearson K, Valentine J, Fuller P, Fell M, Tsuchiya T, Williamson T, Wollenberg G. Miller GK, et al. Among authors: fell m. Toxicol Pathol. 2023 Jul;51(5):232-245. doi: 10.1177/01926233231205895. Epub 2023 Nov 2. Toxicol Pathol. 2023. PMID: 37916535
Sidedness in Unilateral Orofacial Clefts: A Systematic Scoping Review.
Fell M, Bradley D, Chadha A, Butterworth S, Davies A, Russell C, Richard B, Wren Y, Lewis S, Chong D. Fell M, et al. Cleft Palate Craniofac J. 2023 Dec 13:10556656231221027. doi: 10.1177/10556656231221027. Online ahead of print. Cleft Palate Craniofac J. 2023. PMID: 38092732 Free article.
117 results