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A novel antibiotic class targeting the lipopolysaccharide transporter.
Zampaloni C, Mattei P, Bleicher K, Winther L, Thäte C, Bucher C, Adam JM, Alanine A, Amrein KE, Baidin V, Bieniossek C, Bissantz C, Boess F, Cantrill C, Clairfeuille T, Dey F, Di Giorgio P, du Castel P, Dylus D, Dzygiel P, Felici A, García-Alcalde F, Haldimann A, Leipner M, Leyn S, Louvel S, Misson P, Osterman A, Pahil K, Rigo S, Schäublin A, Scharf S, Schmitz P, Stoll T, Trauner A, Zoffmann S, Kahne D, Young JAT, Lobritz MA, Bradley KA. Zampaloni C, et al. Among authors: felici a. Nature. 2024 Jan;625(7995):566-571. doi: 10.1038/s41586-023-06873-0. Epub 2024 Jan 3. Nature. 2024. PMID: 38172634 Free PMC article.
Targeting virulence regulation to disarm Acinetobacter baumannii pathogenesis.
Trebosc V, Lucchini V, Narwal M, Wicki B, Gartenmann S, Schellhorn B, Schill J, Bourotte M, Frey D, Grünberg J, Trauner A, Ferrari L, Felici A, Champion OL, Gitzinger M, Lociuro S, Kammerer RA, Kemmer C, Pieren M. Trebosc V, et al. Among authors: felici a. Virulence. 2022 Dec;13(1):1868-1883. doi: 10.1080/21505594.2022.2135273. Virulence. 2022. PMID: 36261919 Free PMC article.
Tackling recalcitrant Pseudomonas aeruginosa infections in critical illness via anti-virulence monotherapy.
Singh VK, Almpani M, Maura D, Kitao T, Ferrari L, Fontana S, Bergamini G, Calcaterra E, Pignaffo C, Negri M, de Oliveira Pereira T, Skinner F, Gkikas M, Andreotti D, Felici A, Déziel E, Lépine F, Rahme LG. Singh VK, et al. Among authors: felici a. Nat Commun. 2022 Aug 30;13(1):5103. doi: 10.1038/s41467-022-32833-9. Nat Commun. 2022. PMID: 36042245 Free PMC article.
Mouse pneumonia model by Acinetobacter baumannii multidrug resistant strains: Comparison between intranasal inoculation, intratracheal instillation and oropharyngeal aspiration techniques.
Bergamini G, Perico ME, Di Palma S, Sabatini D, Andreetta F, Defazio R, Felici A, Ferrari L. Bergamini G, et al. Among authors: felici a. PLoS One. 2021 Dec 2;16(12):e0260627. doi: 10.1371/journal.pone.0260627. eCollection 2021. PLoS One. 2021. PMID: 34855837 Free PMC article.
Polypharmacology Approaches against the Pseudomonas aeruginosa MvfR Regulon and Their Application in Blocking Virulence and Antibiotic Tolerance.
Maura D, Drees SL, Bandyopadhaya A, Kitao T, Negri M, Starkey M, Lesic B, Milot S, Déziel E, Zahler R, Pucci M, Felici A, Fetzner S, Lépine F, Rahme LG. Maura D, et al. Among authors: felici a. ACS Chem Biol. 2017 May 19;12(5):1435-1443. doi: 10.1021/acschembio.6b01139. Epub 2017 Apr 12. ACS Chem Biol. 2017. PMID: 28379691
Clinical characteristics, treatment, trajectories and outcome of patients with dilated cardiomyopathy in a national heart failure registry.
Carigi S, Gentile P, Gori M, Tinti D, De Gennaro L, Leonardi G, Orso F, Felici AR, Catalano MR, Floresta M, Rizzello V, Lucci D, Gonzini L, De Maria R, Marini M; IN-HF investigators (appendix). Carigi S, et al. Among authors: felici ar. Int J Cardiol. 2024 Jul 15;407:131986. doi: 10.1016/j.ijcard.2024.131986. Epub 2024 Mar 19. Int J Cardiol. 2024. PMID: 38513737
317 results