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Sphingomyelin synthase 1 mediates hepatocyte pyroptosis to trigger non-alcoholic steatohepatitis.
Koh EH, Yoon JE, Ko MS, Leem J, Yun JY, Hong CH, Cho YK, Lee SE, Jang JE, Baek JY, Yoo HJ, Kim SJ, Sung CO, Lim JS, Jeong WI, Back SH, Baek IJ, Torres S, Solsona-Vilarrasa E, Conde de la Rosa L, Garcia-Ruiz C, Feldstein AE, Fernandez-Checa JC, Lee KU. Koh EH, et al. Among authors: feldstein ae. Gut. 2021 Oct;70(10):1954-1964. doi: 10.1136/gutjnl-2020-322509. Epub 2020 Nov 18. Gut. 2021. PMID: 33208407 Free PMC article.
Hepatocyte pyroptosis and release of inflammasome particles induce stellate cell activation and liver fibrosis.
Gaul S, Leszczynska A, Alegre F, Kaufmann B, Johnson CD, Adams LA, Wree A, Damm G, Seehofer D, Calvente CJ, Povero D, Kisseleva T, Eguchi A, McGeough MD, Hoffman HM, Pelegrin P, Laufs U, Feldstein AE. Gaul S, et al. Among authors: feldstein ae. J Hepatol. 2021 Jan;74(1):156-167. doi: 10.1016/j.jhep.2020.07.041. Epub 2020 Aug 4. J Hepatol. 2021. PMID: 32763266 Free PMC article.
Pyroptosis in Steatohepatitis and Liver Diseases.
Knorr J, Wree A, Feldstein AE. Knorr J, et al. Among authors: feldstein ae. J Mol Biol. 2022 Feb 28;434(4):167271. doi: 10.1016/j.jmb.2021.167271. Epub 2021 Sep 27. J Mol Biol. 2022. PMID: 34592216 Free article. Review.
Beneficial effects of mineralocorticoid receptor blockade in experimental non-alcoholic steatohepatitis.
Pizarro M, Solís N, Quintero P, Barrera F, Cabrera D, Rojas-de Santiago P, Arab JP, Padilla O, Roa JC, Moshage H, Wree A, Inzaugarat E, Feldstein AE, Fardella CE, Baudrand R, Riquelme A, Arrese M. Pizarro M, et al. Among authors: feldstein ae. Liver Int. 2015 Sep;35(9):2129-38. doi: 10.1111/liv.12794. Epub 2015 Feb 23. Liver Int. 2015. PMID: 25646700 Free PMC article.
222 results