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A non-canonical vitamin K cycle is a potent ferroptosis suppressor.
Mishima E, Ito J, Wu Z, Nakamura T, Wahida A, Doll S, Tonnus W, Nepachalovich P, Eggenhofer E, Aldrovandi M, Henkelmann B, Yamada KI, Wanninger J, Zilka O, Sato E, Feederle R, Hass D, Maida A, Mourão ASD, Linkermann A, Geissler EK, Nakagawa K, Abe T, Fedorova M, Proneth B, Pratt DA, Conrad M. Mishima E, et al. Among authors: feederle r. Nature. 2022 Aug;608(7924):778-783. doi: 10.1038/s41586-022-05022-3. Epub 2022 Aug 3. Nature. 2022. PMID: 35922516 Free PMC article.
Loss of the cystine/glutamate antiporter in melanoma abrogates tumor metastasis and markedly increases survival rates of mice.
Sato M, Onuma K, Domon M, Hasegawa S, Suzuki A, Kusumi R, Hino R, Kakihara N, Kanda Y, Osaki M, Hamada J, Bannai S, Feederle R, Buday K, Angeli JPF, Proneth B, Conrad M, Okada F, Sato H. Sato M, et al. Among authors: feederle r. Int J Cancer. 2020 Dec 1;147(11):3224-3235. doi: 10.1002/ijc.33262. Epub 2020 Aug 26. Int J Cancer. 2020. PMID: 32818320 Free article.
Inceptor counteracts insulin signalling in β-cells to control glycaemia.
Ansarullah, Jain C, Far FF, Homberg S, Wißmiller K, von Hahn FG, Raducanu A, Schirge S, Sterr M, Bilekova S, Siehler J, Wiener J, Oppenländer L, Morshedi A, Bastidas-Ponce A, Collden G, Irmler M, Beckers J, Feuchtinger A, Grzybek M, Ahlbrecht C, Feederle R, Plettenburg O, Müller TD, Meier M, Tschöp MH, Coskun Ü, Lickert H. Ansarullah, et al. Among authors: feederle r. Nature. 2021 Feb;590(7845):326-331. doi: 10.1038/s41586-021-03225-8. Epub 2021 Jan 27. Nature. 2021. PMID: 33505018
MS4A15 drives ferroptosis resistance through calcium-restricted lipid remodeling.
Xin S, Mueller C, Pfeiffer S, Kraft VAN, Merl-Pham J, Bao X, Feederle R, Jin X, Hauck SM, Schmitt-Kopplin P, Schick JA. Xin S, et al. Among authors: feederle r. Cell Death Differ. 2022 Mar;29(3):670-686. doi: 10.1038/s41418-021-00883-z. Epub 2021 Oct 18. Cell Death Differ. 2022. PMID: 34663908 Free PMC article.
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.
Rehage N, Davydova E, Conrad C, Behrens G, Maiser A, Stehklein JE, Brenner S, Klein J, Jeridi A, Hoffmann A, Lee E, Dianzani U, Willemsen R, Feederle R, Reiche K, Hackermüller J, Leonhardt H, Sharma S, Niessing D, Heissmeyer V. Rehage N, et al. Among authors: feederle r. Nat Commun. 2018 Jan 19;9(1):299. doi: 10.1038/s41467-017-02582-1. Nat Commun. 2018. PMID: 29352114 Free PMC article.
The centrosome protein AKNA regulates neurogenesis via microtubule organization.
Camargo Ortega G, Falk S, Johansson PA, Peyre E, Broix L, Sahu SK, Hirst W, Schlichthaerle T, De Juan Romero C, Draganova K, Vinopal S, Chinnappa K, Gavranovic A, Karakaya T, Steininger T, Merl-Pham J, Feederle R, Shao W, Shi SH, Hauck SM, Jungmann R, Bradke F, Borrell V, Geerlof A, Reber S, Tiwari VK, Huttner WB, Wilsch-Bräuninger M, Nguyen L, Götz M. Camargo Ortega G, et al. Among authors: feederle r. Nature. 2019 Mar;567(7746):113-117. doi: 10.1038/s41586-019-0962-4. Epub 2019 Feb 20. Nature. 2019. PMID: 30787442 Free article.
Mouse brain proteomics establishes MDGA1 and CACHD1 as in vivo substrates of the Alzheimer protease BACE1.
Rudan Njavro J, Klotz J, Dislich B, Wanngren J, Shmueli MD, Herber J, Kuhn PH, Kumar R, Koeglsperger T, Conrad M, Wurst W, Feederle R, Vlachos A, Michalakis S, Jedlicka P, Müller SA, Lichtenthaler SF. Rudan Njavro J, et al. Among authors: feederle r. FASEB J. 2020 Feb;34(2):2465-2482. doi: 10.1096/fj.201902347R. Epub 2019 Dec 27. FASEB J. 2020. PMID: 31908000 Free article.
Spt6 is a maintenance factor for centromeric CENP-A.
Bobkov GOM, Huang A, van den Berg SJW, Mitra S, Anselm E, Lazou V, Schunter S, Feederle R, Imhof A, Lusser A, Jansen LET, Heun P. Bobkov GOM, et al. Among authors: feederle r. Nat Commun. 2020 Jun 10;11(1):2919. doi: 10.1038/s41467-020-16695-7. Nat Commun. 2020. PMID: 32522980 Free PMC article.
123 results