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Targeting the TCA cycle can ameliorate widespread axonal energy deficiency in neuroinflammatory lesions.
Tai YH, Engels D, Locatelli G, Emmanouilidis I, Fecher C, Theodorou D, Müller SA, Licht-Mayer S, Kreutzfeldt M, Wagner I, de Mello NP, Gkotzamani SN, Trovò L, Kendirli A, Aljović A, Breckwoldt MO, Naumann R, Bareyre FM, Perocchi F, Mahad D, Merkler D, Lichtenthaler SF, Kerschensteiner M, Misgeld T. Tai YH, et al. Among authors: fecher c. Nat Metab. 2023 Aug;5(8):1364-1381. doi: 10.1038/s42255-023-00838-3. Epub 2023 Jul 10. Nat Metab. 2023. PMID: 37430025 Free PMC article.
Cell-type-specific profiling of brain mitochondria reveals functional and molecular diversity.
Fecher C, Trovò L, Müller SA, Snaidero N, Wettmarshausen J, Heink S, Ortiz O, Wagner I, Kühn R, Hartmann J, Karl RM, Konnerth A, Korn T, Wurst W, Merkler D, Lichtenthaler SF, Perocchi F, Misgeld T. Fecher C, et al. Nat Neurosci. 2019 Oct;22(10):1731-1742. doi: 10.1038/s41593-019-0479-z. Epub 2019 Sep 9. Nat Neurosci. 2019. PMID: 31501572
Super-resolution microscopy writ large.
Engerer P, Fecher C, Misgeld T. Engerer P, et al. Among authors: fecher c. Nat Biotechnol. 2016 Sep 8;34(9):928-30. doi: 10.1038/nbt.3669. Nat Biotechnol. 2016. PMID: 27606457 No abstract available.
Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal.
Baumann T, Dunkel A, Schmid C, Schmitt S, Hiltensperger M, Lohr K, Laketa V, Donakonda S, Ahting U, Lorenz-Depiereux B, Heil JE, Schredelseker J, Simeoni L, Fecher C, Körber N, Bauer T, Hüser N, Hartmann D, Laschinger M, Eyerich K, Eyerich S, Anton M, Streeter M, Wang T, Schraven B, Spiegel D, Assaad F, Misgeld T, Zischka H, Murray PJ, Heine A, Heikenwälder M, Korn T, Dawid C, Hofmann T, Knolle PA, Höchst B. Baumann T, et al. Among authors: fecher c. Nat Immunol. 2020 May;21(5):555-566. doi: 10.1038/s41590-020-0666-9. Epub 2020 Apr 23. Nat Immunol. 2020. PMID: 32327756
CCL17-expressing dendritic cells drive atherosclerosis by restraining regulatory T cell homeostasis in mice.
Weber C, Meiler S, Döring Y, Koch M, Drechsler M, Megens RT, Rowinska Z, Bidzhekov K, Fecher C, Ribechini E, van Zandvoort MA, Binder CJ, Jelinek I, Hristov M, Boon L, Jung S, Korn T, Lutz MB, Förster I, Zenke M, Hieronymus T, Junt T, Zernecke A. Weber C, et al. Among authors: fecher c. J Clin Invest. 2011 Jul;121(7):2898-910. doi: 10.1172/JCI44925. J Clin Invest. 2011. PMID: 21633167 Free PMC article.
Fast and Deep Phosphoproteome Analysis with the Orbitrap Astral Mass Spectrometer.
Lancaster NM, Sinitcyn P, Forny P, Peters-Clarke TM, Fecher C, Smith AJ, Shishkova E, Arrey TN, Pashkova A, Robinson ML, Arp N, Fan J, Hansen J, Galmozzi A, Serrano LR, Westphall MS, Stewart H, Hock C, Damoc E, Pagliarini DJ, Zabrouskov V, Coon JJ. Lancaster NM, et al. Among authors: fecher c. bioRxiv [Preprint]. 2023 Dec 14:2023.11.21.568149. doi: 10.1101/2023.11.21.568149. bioRxiv. 2023. PMID: 38045259 Free PMC article. Preprint.