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Probing the Interaction of Aspergillomarasmine A with Metallo-β-lactamases NDM-1, VIM-2, and IMP-7.
Bergstrom A, Katko A, Adkins Z, Hill J, Cheng Z, Burnett M, Yang H, Aitha M, Mehaffey MR, Brodbelt JS, Tehrani KHME, Martin NI, Bonomo RA, Page RC, Tierney DL, Fast W, Wright GD, Crowder MW. Bergstrom A, et al. Among authors: fast w. ACS Infect Dis. 2018 Feb 9;4(2):135-145. doi: 10.1021/acsinfecdis.7b00106. Epub 2017 Nov 9. ACS Infect Dis. 2018. PMID: 29091730 Free PMC article.
B1-Metallo-β-Lactamases: Where Do We Stand?
Mojica MF, Bonomo RA, Fast W. Mojica MF, et al. Among authors: fast w. Curr Drug Targets. 2016;17(9):1029-50. doi: 10.2174/1389450116666151001105622. Curr Drug Targets. 2016. PMID: 26424398 Free PMC article. Review.
Dipicolinic Acid Derivatives as Inhibitors of New Delhi Metallo-β-lactamase-1.
Chen AY, Thomas PW, Stewart AC, Bergstrom A, Cheng Z, Miller C, Bethel CR, Marshall SH, Credille CV, Riley CL, Page RC, Bonomo RA, Crowder MW, Tierney DL, Fast W, Cohen SM. Chen AY, et al. Among authors: fast w. J Med Chem. 2017 Sep 14;60(17):7267-7283. doi: 10.1021/acs.jmedchem.7b00407. Epub 2017 Aug 30. J Med Chem. 2017. PMID: 28809565 Free PMC article.
Clinical Variants of New Delhi Metallo-β-Lactamase Are Evolving To Overcome Zinc Scarcity.
Stewart AC, Bethel CR, VanPelt J, Bergstrom A, Cheng Z, Miller CG, Williams C, Poth R, Morris M, Lahey O, Nix JC, Tierney DL, Page RC, Crowder MW, Bonomo RA, Fast W. Stewart AC, et al. Among authors: fast w. ACS Infect Dis. 2017 Dec 8;3(12):927-940. doi: 10.1021/acsinfecdis.7b00128. Epub 2017 Oct 11. ACS Infect Dis. 2017. PMID: 28965402 Free PMC article.
A Single Salt Bridge in VIM-20 Increases Protein Stability and Antibiotic Resistance under Low-Zinc Conditions.
Cheng Z, Shurina BA, Bethel CR, Thomas PW, Marshall SH, Thomas CA, Yang K, Kimble RL, Montgomery JS, Orischak MG, Miller CM, Tennenbaum JL, Nix JC, Tierney DL, Fast W, Bonomo RA, Page RC, Crowder MW. Cheng Z, et al. Among authors: fast w. mBio. 2019 Nov 19;10(6):e02412-19. doi: 10.1128/mBio.02412-19. mBio. 2019. PMID: 31744917 Free PMC article.
Evolution of New Delhi metallo-β-lactamase (NDM) in the clinic: Effects of NDM mutations on stability, zinc affinity, and mono-zinc activity.
Cheng Z, Thomas PW, Ju L, Bergstrom A, Mason K, Clayton D, Miller C, Bethel CR, VanPelt J, Tierney DL, Page RC, Bonomo RA, Fast W, Crowder MW. Cheng Z, et al. Among authors: fast w. J Biol Chem. 2018 Aug 10;293(32):12606-12618. doi: 10.1074/jbc.RA118.003835. Epub 2018 Jun 16. J Biol Chem. 2018. PMID: 29909397 Free PMC article.
77 results