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Macromolecular assemblies: Molecular mechanisms abound.
Fass D, Xu Y. Fass D, et al. Curr Opin Struct Biol. 2023 Aug;81:102639. doi: 10.1016/j.sbi.2023.102639. Epub 2023 Jun 25. Curr Opin Struct Biol. 2023. PMID: 37369162 No abstract available.
Shearing of surface mucin saps tumor cell strength.
Greenberg LJ, Fass D. Greenberg LJ, et al. Among authors: fass d. Trends Pharmacol Sci. 2023 Nov;44(11):755-757. doi: 10.1016/j.tips.2023.08.011. Epub 2023 Sep 5. Trends Pharmacol Sci. 2023. PMID: 37679271 Free article.
Epigenetic modulation through BET bromodomain inhibitors as a novel therapeutic strategy for progranulin-deficient frontotemporal dementia.
Rosenthal ZC, Fass DM, Payne NC, She A, Patnaik D, Hennig KM, Tesla R, Werthmann GC, Guhl C, Reis SA, Wang X, Chen Y, Placzek M, Williams NS, Hooker J, Herz J, Mazitschek R, Haggarty SJ. Rosenthal ZC, et al. Among authors: fass dm. Sci Rep. 2024 Apr 20;14(1):9064. doi: 10.1038/s41598-024-59110-7. Sci Rep. 2024. PMID: 38643236 Free PMC article.
VWD domain stabilization by autocatalytic Asp-Pro cleavage.
Yeshaya N, Gupta PK, Dym O, Morgenstern D, Major DT, Fass D. Yeshaya N, et al. Among authors: fass d. Protein Sci. 2024 Mar;33(3):e4929. doi: 10.1002/pro.4929. Protein Sci. 2024. PMID: 38380729 Free PMC article.
Diversity of CysD domains in gel-forming mucins.
Khmelnitsky L, Milo A, Dym O, Fass D. Khmelnitsky L, et al. Among authors: fass d. FEBS J. 2023 Nov;290(21):5196-5203. doi: 10.1111/febs.16918. Epub 2023 Aug 11. FEBS J. 2023. PMID: 37526947
Intestinal mucin is a chaperone of multivalent copper.
Reznik N, Gallo AD, Rush KW, Javitt G, Fridmann-Sirkis Y, Ilani T, Nairner NA, Fishilevich S, Gokhman D, Chacón KN, Franz KJ, Fass D. Reznik N, et al. Among authors: fass d. Cell. 2022 Oct 27;185(22):4206-4215.e11. doi: 10.1016/j.cell.2022.09.021. Epub 2022 Oct 6. Cell. 2022. PMID: 36206754 Free article.
261 results