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Definition of Haptens Derived from Sulfamethoxazole: In Vitro and in Vivo.
Tailor A, Waddington JC, Hamlett J, Maggs J, Kafu L, Farrell J, Dear GJ, Whitaker P, Naisbitt DJ, Park K, Meng X. Tailor A, et al. Among authors: farrell j. Chem Res Toxicol. 2019 Oct 21;32(10):2095-2106. doi: 10.1021/acs.chemrestox.9b00282. Epub 2019 Sep 11. Chem Res Toxicol. 2019. PMID: 31468968
Direct evidence for the formation of diastereoisomeric benzylpenicilloyl haptens from benzylpenicillin and benzylpenicillenic acid in patients.
Meng X, Jenkins RE, Berry NG, Maggs JL, Farrell J, Lane CS, Stachulski AV, French NS, Naisbitt DJ, Pirmohamed M, Park BK. Meng X, et al. Among authors: farrell j. J Pharmacol Exp Ther. 2011 Sep;338(3):841-9. doi: 10.1124/jpet.111.183871. Epub 2011 Jun 16. J Pharmacol Exp Ther. 2011. PMID: 21680886 Free PMC article.
β-Lactam antibiotics form distinct haptenic structures on albumin and activate drug-specific T-lymphocyte responses in multiallergic patients with cystic fibrosis.
Jenkins RE, Yaseen FS, Monshi MM, Whitaker P, Meng X, Farrell J, Hamlett J, Sanderson JP, El-Ghaiesh S, Peckham D, Pirmohamed M, Park BK, Naisbitt DJ. Jenkins RE, et al. Among authors: farrell j. Chem Res Toxicol. 2013 Jun 17;26(6):963-75. doi: 10.1021/tx400124m. Epub 2013 May 23. Chem Res Toxicol. 2013. PMID: 23668298
Dapsone and Nitroso Dapsone Activation of Naı̈ve T-Cells from Healthy Donors.
Alzahrani A, Ogese M, Meng X, Waddington JC, Tailor A, Farrell J, Maggs JL, Betts C, Park BK, Naisbitt D. Alzahrani A, et al. Among authors: farrell j. Chem Res Toxicol. 2017 Dec 18;30(12):2174-2186. doi: 10.1021/acs.chemrestox.7b00263. Epub 2017 Oct 31. Chem Res Toxicol. 2017. PMID: 29045131
1,103 results