Fan S - Search Results

1

Inhibition of Autophagy by a Small Molecule through Covalent Modification of the LC3 Protein.

Fan S, Yue L, Wan W, Zhang Y, Zhang B, Otomo C, Li Q, Lin T, Hu J, Xu P, Zhu M, Tao H, Chen Z, Li L, Ding H, Yao Z, Lu J, Wen Y, Zhang N, Tan M, Chen K, Xie Y, Otomo T, Zhou B, Jiang H, Dang Y, Luo C. Fan S, et al. Angew Chem Int Ed Engl. 2021 Dec 6;60(50):26105-26114. doi: 10.1002/anie.202109464. Epub 2021 Nov 5. Angew Chem Int Ed Engl. 2021. PMID: 34590387 Free PMC article.

2

Development and evaluation of a novel series of Nitroxoline-derived BET inhibitors with antitumor activity in renal cell carcinoma.

Chen W, Zhang H, Chen Z, Jiang H, Liao L, Fan S, Xing J, Xie Y, Chen S, Ding H, Chen K, Jiang H, Luo C, Zheng M, Yao Z, Huang Y, Zhang Y. Chen W, et al. Among authors: fan s. Oncogenesis. 2018 Nov 2;7(11):83. doi: 10.1038/s41389-018-0093-z. Oncogenesis. 2018. PMID: 30385738 Free PMC article.

3

Machine Learning Methods in Precision Medicine Targeting Epigenetic Diseases.

Fan S, Chen Y, Luo C, Meng F. Fan S, et al. Curr Pharm Des. 2018;24(34):3998-4006. doi: 10.2174/1381612824666181112114228. Curr Pharm Des. 2018. PMID: 30421670 Review.

4

The dynamic conformational landscape of the protein methyltransferase SETD8.

Chen S, Wiewiora RP, Meng F, Babault N, Ma A, Yu W, Qian K, Hu H, Zou H, Wang J, Fan S, Blum G, Pittella-Silva F, Beauchamp KA, Tempel W, Jiang H, Chen K, Skene RJ, Zheng YG, Brown PJ, Jin J, Luo C, Chodera JD, Luo M. Chen S, et al. Among authors: fan s. Elife. 2019 May 13;8:e45403. doi: 10.7554/eLife.45403. Elife. 2019. PMID: 31081496 Free PMC article.

5

Histone deacetylase inhibitor givinostat alleviates liver fibrosis by regulating hepatic stellate cell activation.

Huang HM, Zhou XR, Liu YJ, Fan SJ, Liao LP, Huang J, Shi CC, Yu L, Pen JJ, Luo C, Zhang YY, Li GM. Huang HM, et al. Mol Med Rep. 2021 May;23(5):305. doi: 10.3892/mmr.2021.11944. Epub 2021 Mar 2. Mol Med Rep. 2021. PMID: 33649839 Free PMC article.

6

Cyclin-dependent kinase inhibitor roscovitine attenuates liver inflammation and fibrosis by influencing initiating steps of liver injury.

Liu Y, Li J, Liao L, Huang H, Fan S, Fu R, Huang J, Shi C, Yu L, Chen KX, Zhang YY, Luo C, Li GM. Liu Y, et al. Among authors: fan s. Clin Sci (Lond). 2021 Apr 16;135(7):925-941. doi: 10.1042/CS20201111. Clin Sci (Lond). 2021. PMID: 33786590

7

P300/CBP inhibition sensitizes mantle cell lymphoma to PI3Kδ inhibitor idelalisib.

Zhou XR, Li X, Liao LP, Han J, Huang J, Li JC, Tao HR, Fan SJ, Chen ZF, Li Q, Chen SJ, Ding H, Yang YX, Zhou B, Jiang HL, Chen KX, Zhang YY, Huang CX, Luo C. Zhou XR, et al. Acta Pharmacol Sin. 2022 Feb;43(2):457-469. doi: 10.1038/s41401-021-00643-2. Epub 2021 Apr 13. Acta Pharmacol Sin. 2022. PMID: 33850273 Free PMC article.

8

Structure-Guided Development of Small-Molecule PRC2 Inhibitors Targeting EZH2-EED Interaction.

Du D, Xu D, Zhu L, Stazi G, Zwergel C, Liu Y, Luo Z, Li Y, Zhang Y, Zhu K, Ding Y, Liu J, Fan S, Zhao K, Zhang N, Kong X, Jiang H, Chen K, Zhao K, Valente S, Min J, Duan W, Luo C. Du D, et al. Among authors: fan s. J Med Chem. 2021 Jun 24;64(12):8194-8207. doi: 10.1021/acs.jmedchem.0c02261. Epub 2021 Jun 2. J Med Chem. 2021. PMID: 34077206

9

Histone deacetylase inhibitor givinostat attenuates nonalcoholic steatohepatitis and liver fibrosis.

Huang HM, Fan SJ, Zhou XR, Liu YJ, Li X, Liao LP, Huang J, Shi CC, Yu L, Fu R, Fan JG, Zhang YY, Luo C, Li GM. Huang HM, et al. Acta Pharmacol Sin. 2022 Apr;43(4):941-953. doi: 10.1038/s41401-021-00725-1. Epub 2021 Aug 2. Acta Pharmacol Sin. 2022. PMID: 34341511 Free PMC article.

10

Cyclization strategy leads to highly potent Bromodomain and extra-terminal (BET) Bromodomain inhibitors for the treatment of acute liver injury.

Chen C, Lu T, Chen P, Li Z, Yang Y, Fan S, Zhang Y, Chen K, Fu W, Wang Y, Luo C, Zhou B. Chen C, et al. Among authors: fan s. Eur J Med Chem. 2023 Feb 5;247:115023. doi: 10.1016/j.ejmech.2022.115023. Epub 2022 Dec 16. Eur J Med Chem. 2023. PMID: 36566713

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