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ATM-CHK2-Beclin 1 axis promotes autophagy to maintain ROS homeostasis under oxidative stress.
Guo QQ, Wang SS, Zhang SS, Xu HD, Li XM, Guan Y, Yi F, Zhou TT, Jiang B, Bai N, Ma MT, Wang Z, Feng YL, Guo WD, Wu X, Zhao GF, Fan GJ, Zhang SP, Wang CG, Cao LY, O'Rourke BP, Liu SH, Wang PY, Han S, Song XY, Cao L. Guo QQ, et al. Among authors: fan gj. EMBO J. 2020 May 18;39(10):e103111. doi: 10.15252/embj.2019103111. Epub 2020 Mar 18. EMBO J. 2020. PMID: 32187724 Free PMC article.
The REGγ proteasome regulates hepatic lipid metabolism through inhibition of autophagy.
Dong S, Jia C, Zhang S, Fan G, Li Y, Shan P, Sun L, Xiao W, Li L, Zheng Y, Liu J, Wei H, Hu C, Zhang W, Chin YE, Zhai Q, Li Q, Liu J, Jia F, Mo Q, Edwards DP, Huang S, Chan L, O'Malley BW, Li X, Wang C. Dong S, et al. Cell Metab. 2013 Sep 3;18(3):380-91. doi: 10.1016/j.cmet.2013.08.012. Cell Metab. 2013. PMID: 24011073 Free PMC article.
Loss of KLF14 triggers centrosome amplification and tumorigenesis.
Fan G, Sun L, Shan P, Zhang X, Huan J, Zhang X, Li D, Wang T, Wei T, Zhang X, Gu X, Yao L, Xuan Y, Hou Z, Cui Y, Cao L, Li X, Zhang S, Wang C. Fan G, et al. Nat Commun. 2015 Oct 6;6:8450. doi: 10.1038/ncomms9450. Nat Commun. 2015. PMID: 26439168 Free PMC article.
The deacetylation-phosphorylation regulation of SIRT2-SMC1A axis as a mechanism of antimitotic catastrophe in early tumorigenesis.
Yi F, Zhang Y, Wang Z, Wang Z, Li Z, Zhou T, Xu H, Liu J, Jiang B, Li X, Wang L, Bai N, Guo Q, Guan Y, Feng Y, Mao Z, Fan G, Zhang S, Wang C, Cao L, O'Rourke BP, Wang Y, Wu Y, Wu B, You S, Zhang N, Guan J, Song X, Sun Y, Wei S, Cao L. Yi F, et al. Sci Adv. 2021 Feb 24;7(9):eabe5518. doi: 10.1126/sciadv.abe5518. Print 2021 Feb. Sci Adv. 2021. PMID: 33627431 Free PMC article.
OTUB1 alleviates NASH through inhibition of the TRAF6-ASK1 signaling pathways.
Zhang JL, Du BB, Zhang DH, Li H, Kong LY, Fan GJ, Li YP, Li PC, Liang C, Wang Z, Yang LL, Hao ZY, Wu LM, Huang Z, Dong JZ, Zhang JY, Yao R, Wang SJ, Zhang YZ. Zhang JL, et al. Among authors: fan gj. Hepatology. 2022 May;75(5):1218-1234. doi: 10.1002/hep.32179. Epub 2021 Dec 7. Hepatology. 2022. PMID: 34591986
69 results