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Genome-wide association study identifies 30 loci associated with bipolar disorder.
Stahl EA, Breen G, Forstner AJ, McQuillin A, Ripke S, Trubetskoy V, Mattheisen M, Wang Y, Coleman JRI, Gaspar HA, de Leeuw CA, Steinberg S, Pavlides JMW, Trzaskowski M, Byrne EM, Pers TH, Holmans PA, Richards AL, Abbott L, Agerbo E, Akil H, Albani D, Alliey-Rodriguez N, Als TD, Anjorin A, Antilla V, Awasthi S, Badner JA, Bækvad-Hansen M, Barchas JD, Bass N, Bauer M, Belliveau R, Bergen SE, Pedersen CB, Bøen E, Boks MP, Boocock J, Budde M, Bunney W, Burmeister M, Bybjerg-Grauholm J, Byerley W, Casas M, Cerrato F, Cervantes P, Chambert K, Charney AW, Chen D, Churchhouse C, Clarke TK, Coryell W, Craig DW, Cruceanu C, Curtis D, Czerski PM, Dale AM, de Jong S, Degenhardt F, Del-Favero J, DePaulo JR, Djurovic S, Dobbyn AL, Dumont A, Elvsåshagen T, Escott-Price V, Fan CC, Fischer SB, Flickinger M, Foroud TM, Forty L, Frank J, Fraser C, Freimer NB, Frisén L, Gade K, Gage D, Garnham J, Giambartolomei C, Pedersen MG, Goldstein J, Gordon SD, Gordon-Smith K, Green EK, Green MJ, Greenwood TA, Grove J, Guan W, Guzman-Parra J, Hamshere ML, Hautzinger M, Heilbronner U, Herms S, Hipolito M, Hoffmann P, Holland D, Huckins L, Jamain S, Johnson JS, Juréus A, Kandaswamy R, Karlsson R, Kennedy J… See abstract for full author list ➔ Stahl EA, et al. Among authors: fan cc. Nat Genet. 2019 May;51(5):793-803. doi: 10.1038/s41588-019-0397-8. Epub 2019 May 1. Nat Genet. 2019. PMID: 31043756 Free PMC article.
Modeling the 3D geometry of the cortical surface with genetic ancestry.
Fan CC, Bartsch H, Schork AJ, Chen CH, Wang Y, Lo MT, Brown TT, Kuperman JM, Hagler DJ Jr, Schork NJ, Jernigan TL, Dale AM; Pediatric Imaging, Neurocognition, and Genetics Study. Fan CC, et al. Curr Biol. 2015 Aug 3;25(15):1988-92. doi: 10.1016/j.cub.2015.06.006. Epub 2015 Jul 9. Curr Biol. 2015. PMID: 26166778 Free PMC article.
Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score.
Desikan RS, Fan CC, Wang Y, Schork AJ, Cabral HJ, Cupples LA, Thompson WK, Besser L, Kukull WA, Holland D, Chen CH, Brewer JB, Karow DS, Kauppi K, Witoelar A, Karch CM, Bonham LW, Yokoyama JS, Rosen HJ, Miller BL, Dillon WP, Wilson DM, Hess CP, Pericak-Vance M, Haines JL, Farrer LA, Mayeux R, Hardy J, Goate AM, Hyman BT, Schellenberg GD, McEvoy LK, Andreassen OA, Dale AM. Desikan RS, et al. Among authors: fan cc. PLoS Med. 2017 Mar 21;14(3):e1002258. doi: 10.1371/journal.pmed.1002258. eCollection 2017 Mar. PLoS Med. 2017. PMID: 28323831 Free PMC article.
Polygenic hazard scores in preclinical Alzheimer disease.
Tan CH, Hyman BT, Tan JJX, Hess CP, Dillon WP, Schellenberg GD, Besser LM, Kukull WA, Kauppi K, McEvoy LK, Andreassen OA, Dale AM, Fan CC, Desikan RS. Tan CH, et al. Among authors: fan cc. Ann Neurol. 2017 Sep;82(3):484-488. doi: 10.1002/ana.25029. Ann Neurol. 2017. PMID: 28940650 Free PMC article.
Polygenic hazard score: an enrichment marker for Alzheimer's associated amyloid and tau deposition.
Tan CH, Fan CC, Mormino EC, Sugrue LP, Broce IJ, Hess CP, Dillon WP, Bonham LW, Yokoyama JS, Karch CM, Brewer JB, Rabinovici GD, Miller BL, Schellenberg GD, Kauppi K, Feldman HA, Holland D, McEvoy LK, Hyman BT, Bennett DA, Andreassen OA, Dale AM, Desikan RS; Alzheimer’s Disease Neuroimaging Initiative. Tan CH, et al. Among authors: fan cc. Acta Neuropathol. 2018 Jan;135(1):85-93. doi: 10.1007/s00401-017-1789-4. Epub 2017 Nov 24. Acta Neuropathol. 2018. PMID: 29177679 Free PMC article.
Beyond heritability: improving discoverability in imaging genetics.
Fan CC, Smeland OB, Schork AJ, Chen CH, Holland D, Lo MT, Sundar VS, Frei O, Jernigan TL, Andreassen OA, Dale AM. Fan CC, et al. Hum Mol Genet. 2018 May 1;27(R1):R22-R28. doi: 10.1093/hmg/ddy082. Hum Mol Genet. 2018. PMID: 29522091 Free PMC article. Review.
A molecule-based genetic association approach implicates a range of voltage-gated calcium channels associated with schizophrenia.
Li W, Fan CC, Mäki-Marttunen T, Thompson WK, Schork AJ, Bettella F; Schizophrenia Working Group of the Psychiatric Genomics Consortium; Djurovic S, Dale AM, Andreassen OA, Wang Y. Li W, et al. Among authors: fan cc. Am J Med Genet B Neuropsychiatr Genet. 2018 Jun;177(4):454-467. doi: 10.1002/ajmg.b.32634. Epub 2018 Apr 28. Am J Med Genet B Neuropsychiatr Genet. 2018. PMID: 29704319 Free PMC article.
Combining Polygenic Hazard Score With Volumetric MRI and Cognitive Measures Improves Prediction of Progression From Mild Cognitive Impairment to Alzheimer's Disease.
Kauppi K, Fan CC, McEvoy LK, Holland D, Tan CH, Chen CH, Andreassen OA, Desikan RS, Dale AM; Alzheimer's Disease Neuroimaging Initiative. Kauppi K, et al. Among authors: fan cc. Front Neurosci. 2018 Apr 30;12:260. doi: 10.3389/fnins.2018.00260. eCollection 2018. Front Neurosci. 2018. PMID: 29760643 Free PMC article.
Williams Syndrome neuroanatomical score associates with GTF2IRD1 in large-scale magnetic resonance imaging cohorts: a proof of concept for multivariate endophenotypes.
Fan CC, Schork AJ, Brown TT, Spencer BE, Akshoomoff N, Chen CH, Kuperman JM, Hagler DJ Jr, Steen VM, Le Hellard S, Håberg AK, Espeseth T, Andreassen OA, Dale AM, Jernigan TL, Halgren E; Pediatric Imaging, Neurocognition and Genetics Study, Alzheimer’s Disease Neuroimaging Initiative. Fan CC, et al. Transl Psychiatry. 2018 Jun 8;8(1):114. doi: 10.1038/s41398-018-0166-y. Transl Psychiatry. 2018. PMID: 29884845 Free PMC article.
257 results