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Empagliflozin improves endothelial and cardiomyocyte function in human heart failure with preserved ejection fraction via reduced pro-inflammatory-oxidative pathways and protein kinase Gα oxidation.
Kolijn D, Pabel S, Tian Y, Lódi M, Herwig M, Carrizzo A, Zhazykbayeva S, Kovács Á, Fülöp GÁ, Falcão-Pires I, Reusch PH, Linthout SV, Papp Z, van Heerebeek L, Vecchione C, Maier LS, Ciccarelli M, Tschöpe C, Mügge A, Bagi Z, Sossalla S, Hamdani N. Kolijn D, et al. Cardiovasc Res. 2021 Jan 21;117(2):495-507. doi: 10.1093/cvr/cvaa123. Cardiovasc Res. 2021. PMID: 32396609
The impact of echocardiographic indexation to evaluate cardiac reverse remodeling throughout pregnancy and postpartum.
Ferreira AF, Saraiva F, Diaz SO, Azevedo MJ, Sousa C, Leite-Moreira A, Sampaio-Maia B, Ramalho C, Barros AS, Falcão-Pires I. Ferreira AF, et al. Among authors: falcao pires i. Rev Port Cardiol. 2024 Mar;43(3):107-127. doi: 10.1016/j.repc.2023.04.014. Epub 2023 Jul 24. Rev Port Cardiol. 2024. PMID: 37495102 Free article. English, Portuguese.
Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension.
van Heerebeek L, Hamdani N, Handoko ML, Falcao-Pires I, Musters RJ, Kupreishvili K, Ijsselmuiden AJ, Schalkwijk CG, Bronzwaer JG, Diamant M, Borbély A, van der Velden J, Stienen GJ, Laarman GJ, Niessen HW, Paulus WJ. van Heerebeek L, et al. Circulation. 2008 Jan 1;117(1):43-51. doi: 10.1161/CIRCULATIONAHA.107.728550. Epub 2007 Dec 10. Circulation. 2008. PMID: 18071071
Diabetes mellitus worsens diastolic left ventricular dysfunction in aortic stenosis through altered myocardial structure and cardiomyocyte stiffness.
Falcão-Pires I, Hamdani N, Borbély A, Gavina C, Schalkwijk CG, van der Velden J, van Heerebeek L, Stienen GJ, Niessen HW, Leite-Moreira AF, Paulus WJ. Falcão-Pires I, et al. Circulation. 2011 Sep 6;124(10):1151-9. doi: 10.1161/CIRCULATIONAHA.111.025270. Epub 2011 Aug 15. Circulation. 2011. PMID: 21844073 Free article.
Low myocardial protein kinase G activity in heart failure with preserved ejection fraction.
van Heerebeek L, Hamdani N, Falcão-Pires I, Leite-Moreira AF, Begieneman MP, Bronzwaer JG, van der Velden J, Stienen GJ, Laarman GJ, Somsen A, Verheugt FW, Niessen HW, Paulus WJ. van Heerebeek L, et al. Circulation. 2012 Aug 14;126(7):830-9. doi: 10.1161/CIRCULATIONAHA.111.076075. Epub 2012 Jul 17. Circulation. 2012. PMID: 22806632
Myocardial titin hypophosphorylation importantly contributes to heart failure with preserved ejection fraction in a rat metabolic risk model.
Hamdani N, Franssen C, Lourenço A, Falcão-Pires I, Fontoura D, Leite S, Plettig L, López B, Ottenheijm CA, Becher PM, González A, Tschöpe C, Díez J, Linke WA, Leite-Moreira AF, Paulus WJ. Hamdani N, et al. Circ Heart Fail. 2013 Nov;6(6):1239-49. doi: 10.1161/CIRCHEARTFAILURE.113.000539. Epub 2013 Sep 6. Circ Heart Fail. 2013. PMID: 24014826
Echocardiography and invasive hemodynamics during stress testing for diagnosis of heart failure with preserved ejection fraction: an experimental study.
Leite S, Oliveira-Pinto J, Tavares-Silva M, Abdellatif M, Fontoura D, Falcão-Pires I, Leite-Moreira AF, Lourenço AP. Leite S, et al. Am J Physiol Heart Circ Physiol. 2015 Jun 15;308(12):H1556-63. doi: 10.1152/ajpheart.00076.2015. Epub 2015 Apr 10. Am J Physiol Heart Circ Physiol. 2015. PMID: 25862827 Free article.
Afterload-induced diastolic dysfunction contributes to high filling pressures in experimental heart failure with preserved ejection fraction.
Leite S, Rodrigues S, Tavares-Silva M, Oliveira-Pinto J, Alaa M, Abdellatif M, Fontoura D, Falcão-Pires I, Gillebert TC, Leite-Moreira AF, Lourenço AP. Leite S, et al. Am J Physiol Heart Circ Physiol. 2015 Nov 15;309(10):H1648-54. doi: 10.1152/ajpheart.00397.2015. Epub 2015 Sep 25. Am J Physiol Heart Circ Physiol. 2015. PMID: 26408538 Free article.
Distinct Endothelial Cell Responses in the Heart and Kidney Microvasculature Characterize the Progression of Heart Failure With Preserved Ejection Fraction in the Obese ZSF1 Rat With Cardiorenal Metabolic Syndrome.
van Dijk CG, Oosterhuis NR, Xu YJ, Brandt M, Paulus WJ, van Heerebeek L, Duncker DJ, Verhaar MC, Fontoura D, Lourenço AP, Leite-Moreira AF, Falcão-Pires I, Joles JA, Cheng C. van Dijk CG, et al. Circ Heart Fail. 2016 Apr;9(4):e002760. doi: 10.1161/CIRCHEARTFAILURE.115.002760. Circ Heart Fail. 2016. PMID: 27056881
126 results