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On the Hunt for Next-Generation Antimicrobial Agents: An Online Symposium Organized Jointly by the French Society for Medicinal Chemistry (Société de Chimie Thérapeutique) and the French Microbiology Society (Société Française de Microbiologie) on 9-10 December 2021.
Pharmaceuticals (Basel). 2022 Mar 23;15(4):388. doi: 10.3390/ph15040388.
Pharmaceuticals (Basel). 2022.
PMID: 35455385
Free PMC article.
Discovery of the first Mycobacterium tuberculosis MabA (FabG1) inhibitors through a fragment-based screening.
Faïon L, Djaout K, Frita R, Pintiala C, Cantrelle FX, Moune M, Vandeputte A, Bourbiaux K, Piveteau C, Herledan A, Biela A, Leroux F, Kremer L, Blaise M, Tanina A, Wintjens R, Hanoulle X, Déprez B, Willand N, Baulard AR, Flipo M.
Faïon L, et al.
Eur J Med Chem. 2020 Aug 15;200:112440. doi: 10.1016/j.ejmech.2020.112440. Epub 2020 May 18.
Eur J Med Chem. 2020.
PMID: 32505086
Free article.
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Tricyclic SpiroLactams Kill Mycobacteria In Vitro and In Vivo by Inhibiting Type II NADH Dehydrogenases.
Dam S, Tangara S, Hamela C, Hattabi T, Faïon L, Carre P, Antoine R, Herledan A, Leroux F, Piveteau C, Eveque M, Flipo M, Deprez B, Kremer L, Willand N, Villemagne B, Hartkoorn RC.
Dam S, et al. Among authors: faion l.
J Med Chem. 2022 Dec 22;65(24):16651-16664. doi: 10.1021/acs.jmedchem.2c01493. Epub 2022 Dec 6.
J Med Chem. 2022.
PMID: 36473699
Free PMC article.
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Exploring the Antitubercular Activity of Anthranilic Acid Derivatives: From MabA (FabG1) Inhibition to Intrabacterial Acidification.
Faïon L, Djaout K, Pintiala C, Piveteau C, Leroux F, Biela A, Slupek S, Antoine R, Záhorszká M, Cantrelle FX, Hanoulle X, Korduláková J, Deprez B, Willand N, Baulard AR, Flipo M.
Faïon L, et al.
Pharmaceuticals (Basel). 2023 Feb 22;16(3):335. doi: 10.3390/ph16030335.
Pharmaceuticals (Basel). 2023.
PMID: 36986435
Free PMC article.
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Rapid and Efficient Access to Novel Bio-Inspired 3-Dimensional Tricyclic SpiroLactams as Privileged Structures via Meyers' Lactamization.
Tangara S, Faïon L, Piveteau C, Capet F, Godelier R, Michel M, Flipo M, Deprez B, Willand N, Villemagne B.
Tangara S, et al. Among authors: faion l.
Pharmaceuticals (Basel). 2023 Mar 8;16(3):413. doi: 10.3390/ph16030413.
Pharmaceuticals (Basel). 2023.
PMID: 36986512
Free PMC article.
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Recent advances in Fragment-based strategies against tuberculosis.
Villemagne B, Faion L, Tangara S, Willand N.
Villemagne B, et al. Among authors: faion l.
Eur J Med Chem. 2023 Oct 5;258:115569. doi: 10.1016/j.ejmech.2023.115569. Epub 2023 Jun 17.
Eur J Med Chem. 2023.
PMID: 37423127
Review.
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