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Page 1
Frequent loss of heterozygosity in CRISPR-Cas9-edited early human embryos.
Alanis-Lobato G, Zohren J, McCarthy A, Fogarty NME, Kubikova N, Hardman E, Greco M, Wells D, Turner JMA, Niakan KK. Alanis-Lobato G, et al. Proc Natl Acad Sci U S A. 2021 Jun 1;118(22):e2004832117. doi: 10.1073/pnas.2004832117. Epub 2021 Apr 9. Proc Natl Acad Sci U S A. 2021. PMID: 34050011 Free PMC article.
Initiation of a conserved trophectoderm program in human, cow and mouse embryos.
Gerri C, McCarthy A, Alanis-Lobato G, Demtschenko A, Bruneau A, Loubersac S, Fogarty NME, Hampshire D, Elder K, Snell P, Christie L, David L, Van de Velde H, Fouladi-Nashta AA, Niakan KK. Gerri C, et al. Nature. 2020 Nov;587(7834):443-447. doi: 10.1038/s41586-020-2759-x. Epub 2020 Sep 23. Nature. 2020. PMID: 32968278 Free PMC article.
IGF1-mediated human embryonic stem cell self-renewal recapitulates the embryonic niche.
Wamaitha SE, Grybel KJ, Alanis-Lobato G, Gerri C, Ogushi S, McCarthy A, Mahadevaiah SK, Healy L, Lea RA, Molina-Arcas M, Devito LG, Elder K, Snell P, Christie L, Downward J, Turner JMA, Niakan KK. Wamaitha SE, et al. Nat Commun. 2020 Feb 7;11(1):764. doi: 10.1038/s41467-020-14629-x. Nat Commun. 2020. PMID: 32034154 Free PMC article.
Effects of thyroid hormone on mitochondria and metabolism of human preimplantation embryos.
Noli L, Khorsandi SE, Pyle A, Giritharan G, Fogarty N, Capalbo A, Devito L, Jovanovic VM, Khurana P, Rosa H, Kolundzic N, Cvoro A, Niakan KK, Malik A, Foulk R, Heaton N, Ardawi MS, Chinnery PF, Ogilvie C, Khalaf Y, Ilic D. Noli L, et al. Stem Cells. 2020 Mar;38(3):369-381. doi: 10.1002/stem.3129. Epub 2019 Dec 26. Stem Cells. 2020. PMID: 31778245 Free PMC article.
SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice.
Hirota T, Blakeley P, Sangrithi MN, Mahadevaiah SK, Encheva V, Snijders AP, ElInati E, Ojarikre OA, de Rooij DG, Niakan KK, Turner JMA. Hirota T, et al. Dev Cell. 2018 Dec 3;47(5):645-659.e6. doi: 10.1016/j.devcel.2018.10.004. Epub 2018 Nov 1. Dev Cell. 2018. PMID: 30393076 Free PMC article.
Genome editing reveals a role for OCT4 in human embryogenesis.
Fogarty NME, McCarthy A, Snijders KE, Powell BE, Kubikova N, Blakeley P, Lea R, Elder K, Wamaitha SE, Kim D, Maciulyte V, Kleinjung J, Kim JS, Wells D, Vallier L, Bertero A, Turner JMA, Niakan KK. Fogarty NME, et al. Nature. 2017 Oct 5;550(7674):67-73. doi: 10.1038/nature24033. Epub 2017 Sep 20. Nature. 2017. PMID: 28953884 Free PMC article.