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Afadin is required for maintenance of dendritic structure and excitatory tone.
Srivastava DP, Copits BA, Xie Z, Huda R, Jones KA, Mukherji S, Cahill ME, VanLeeuwen JE, Woolfrey KM, Rafalovich I, Swanson GT, Penzes P. Srivastava DP, et al. J Biol Chem. 2012 Oct 19;287(43):35964-74. doi: 10.1074/jbc.M112.363358. Epub 2012 Sep 4. J Biol Chem. 2012. PMID: 22948147 Free PMC article.
Dendritic spine pathology in neuropsychiatric disorders.
Penzes P, Cahill ME, Jones KA, VanLeeuwen JE, Woolfrey KM. Penzes P, et al. Nat Neurosci. 2011 Mar;14(3):285-93. doi: 10.1038/nn.2741. Nat Neurosci. 2011. PMID: 21346746 Free PMC article. Review.
Hippocampal phenotypes in kalirin-deficient mice.
Xie Z, Cahill ME, Radulovic J, Wang J, Campbell SL, Miller CA, Sweatt JD, Penzes P. Xie Z, et al. Mol Cell Neurosci. 2011 Jan;46(1):45-54. doi: 10.1016/j.mcn.2010.08.005. Epub 2010 Aug 11. Mol Cell Neurosci. 2011. PMID: 20708080 Free PMC article.