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Combinatorial Immunotherapy with Agonistic CD40 Activates Dendritic Cells to Express IL12 and Overcomes PD-1 Resistance.
Krykbaeva I, Bridges K, Damsky W, Pizzurro GA, Alexander AF, McGeary MK, Park K, Muthusamy V, Eyles J, Luheshi N, Turner N, Weiss SA, Olino K, Kaech SM, Kluger HM, Miller-Jensen K, Bosenberg M. Krykbaeva I, et al. Among authors: eyles j. Cancer Immunol Res. 2023 Oct 4;11(10):1332-1350. doi: 10.1158/2326-6066.CIR-22-0699. Cancer Immunol Res. 2023. PMID: 37478171
Efficacy and pharmacodynamic effect of anti-CD73 and anti-PD-L1 monoclonal antibodies in combination with cytotoxic therapy: observations from mouse tumor models.
Kaistha BP, Kar G, Dannhorn A, Watkins A, Opoku-Ansah G, Ilieva K, Mullins S, Anderton J, Galvani E, Garcon F, Lapointe JM, Brown L, Hair J, Slidel T, Luheshi N, Ryan K, Hardaker E, Dovedi S, Kumar R, Wilkinson RW, Hammond SA, Eyles J. Kaistha BP, et al. Among authors: eyles j. Cancer Biol Ther. 2024 Dec 31;25(1):2296048. doi: 10.1080/15384047.2023.2296048. Epub 2024 Jan 11. Cancer Biol Ther. 2024. PMID: 38206570 Free PMC article.
Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma.
Graziano V, Dannhorn A, Hulme H, Williamson K, Buckley H, Karim SA, Wilson M, Lee SY, Kaistha BP, Islam S, Thaventhiran JED, Richards FM, Goodwin R, Brais R, Morton JP, Dovedi SJ, Schuller AG, Eyles J, Jodrell DI. Graziano V, et al. Among authors: eyles j. J Immunother Cancer. 2023 Aug;11(8):e006457. doi: 10.1136/jitc-2022-006457. J Immunother Cancer. 2023. PMID: 37553182 Free PMC article.
CD73 controls Myosin II-driven invasion, metastasis, and immunosuppression in amoeboid pancreatic cancer cells.
Samain R, Maiques O, Monger J, Lam H, Candido J, George S, Ferrari N, KohIhammer L, Lunetto S, Varela A, Orgaz JL, Vilardell F, Olsina JJ, Matias-Guiu X, Sarker D, Biddle A, Balkwill FR, Eyles J, Wilkinson RW, Kocher HM, Calvo F, Wells CM, Sanz-Moreno V. Samain R, et al. Among authors: eyles j. Sci Adv. 2023 Oct 20;9(42):eadi0244. doi: 10.1126/sciadv.adi0244. Epub 2023 Oct 18. Sci Adv. 2023. PMID: 37851808 Free PMC article.
Appraisal of quality and analysis of the similarities and differences between osteoarthritis Clinical Practice Guideline recommendations: A systematic review.
Gray B, Gibbs A, Bowden JL, Eyles JP, Grace S, Bennell K, Geenen R, Sharon Kolasinski, Barton C, Conaghan PG, McAlindon T, Bruyere O, Géczy Q, Hunter DJ. Gray B, et al. Among authors: eyles jp. Osteoarthritis Cartilage. 2024 Mar 5:S1063-4584(24)00935-X. doi: 10.1016/j.joca.2024.02.890. Online ahead of print. Osteoarthritis Cartilage. 2024. PMID: 38452880 Free article. Review.
Changing the narrative on osteoarthritis: A call for global action.
Jinks C, Botto-van Bemden A, Bunzli S, Bowden J, Egerton T, Eyles J, Foster N, Healey EL, Maddison J, O'Brien D, Quicke JG, Schiphof D, Parry E, Thomas MJ, Holden MA; Change OA Narrative (COAN) Initiative. Jinks C, et al. Among authors: eyles j. Osteoarthritis Cartilage. 2024 Apr;32(4):414-420. doi: 10.1016/j.joca.2024.02.004. Epub 2024 Feb 12. Osteoarthritis Cartilage. 2024. PMID: 38354847 No abstract available.
Lessons learnt from a nationally funded training and mentoring programme for early-mid career musculoskeletal researchers in Australia.
Lawford BJ, Hinman RS, Bennell KL, Hunter DJ, Hodges PW, Setchell J, Eyles J, Allison K, Campbell P, Mellor R; MUSQ:Impact Steering Committee; Vicenzino B. Lawford BJ, et al. Among authors: eyles j. Musculoskeletal Care. 2023 Dec;21(4):1563-1570. doi: 10.1002/msc.1820. Epub 2023 Oct 16. Musculoskeletal Care. 2023. PMID: 37843259 Free PMC article.
266 results