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Efficacy and safety of edoxaban in patients early after surgical bioprosthetic valve implantation or valve repair: A randomized clinical trial.
Shim CY, Seo J, Kim YJ, Lee SH, De Caterina R, Lee S, Hong GR; Explore the Efficacy and Safety of Edoxaban in Patients after Heart Valve Repair or Bioprosthetic Valve Replacement (ENAVLE) study group. Shim CY, et al. J Thorac Cardiovasc Surg. 2023 Jan;165(1):58-67.e4. doi: 10.1016/j.jtcvs.2021.01.127. Epub 2021 Feb 9. J Thorac Cardiovasc Surg. 2023. PMID: 33726903 Clinical Trial.
It is unclear whether non-vitamin K antagonist oral anticoagulants can be a full alternative to warfarin. This study aimed to compare efficacy and safety of edoxaban with warfarin in patients early after surgical bioprosthetic valve implantation …
It is unclear whether non-vitamin K antagonist oral anticoagulants can be a full alternative to warfarin. This study aimed to compare eff
Valvular Heart Disease Patients on Edoxaban or Warfarin in the ENGAGE AF-TIMI 48 Trial.
De Caterina R, Renda G, Carnicelli AP, Nordio F, Trevisan M, Mercuri MF, Ruff CT, Antman EM, Braunwald E, Giugliano RP. De Caterina R, et al. J Am Coll Cardiol. 2017 Mar 21;69(11):1372-1382. doi: 10.1016/j.jacc.2016.12.031. J Am Coll Cardiol. 2017. PMID: 28302288 Free article. Clinical Trial.
Patients with moderate to severe mitral stenosis or mechanical heart valves were excluded from the trial. Comparisons were made of rates of stroke/systemic embolic event (SSEE), major bleeding, additional efficacy and safety outcomes, as well as
Patients with moderate to severe mitral stenosis or mechanical heart valves were excluded from the trial. Comparisons w