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Evaluation of Cell-Specific Epigenetic Age Acceleration in People With Multiple Sclerosis.
Maltby V, Xavier A, Ewing E, Campagna MP, Sampangi S, Scott RJ, Butzkueven H, Jokubaitis V, Kular L, Bos S, Slee M, van der Mei IA, Taylor BV, Ponsonby AL, Jagodic M, Lea R, Lechner-Scott J. Maltby V, et al. Among authors: ewing e. Neurology. 2023 Aug 15;101(7):e679-e689. doi: 10.1212/WNL.0000000000207489. Epub 2023 Aug 4. Neurology. 2023. PMID: 37541839 Free PMC article.
Epigenetic research in multiple sclerosis: progress, challenges, and opportunities.
Zheleznyakova GY, Piket E, Marabita F, Pahlevan Kakhki M, Ewing E, Ruhrmann S, Needhamsen M, Jagodic M, Kular L. Zheleznyakova GY, et al. Among authors: ewing e. Physiol Genomics. 2017 Sep 1;49(9):447-461. doi: 10.1152/physiolgenomics.00060.2017. Epub 2017 Jul 28. Physiol Genomics. 2017. PMID: 28754822 Review.
Hypermethylation of MIR21 in CD4+ T cells from patients with relapsing-remitting multiple sclerosis associates with lower miRNA-21 levels and concomitant up-regulation of its target genes.
Ruhrmann S, Ewing E, Piket E, Kular L, Cetrulo Lorenzi JC, Fernandes SJ, Morikawa H, Aeinehband S, Sayols-Baixeras S, Aslibekyan S, Absher DM, Arnett DK, Tegner J, Gomez-Cabrero D, Piehl F, Jagodic M. Ruhrmann S, et al. Among authors: ewing e. Mult Scler. 2018 Sep;24(10):1288-1300. doi: 10.1177/1352458517721356. Epub 2017 Aug 2. Mult Scler. 2018. PMID: 28766461 Free PMC article.
Fatal demyelinating disease is induced by monocyte-derived macrophages in the absence of TGF-β signaling.
Lund H, Pieber M, Parsa R, Grommisch D, Ewing E, Kular L, Han J, Zhu K, Nijssen J, Hedlund E, Needhamsen M, Ruhrmann S, Guerreiro-Cacais AO, Berglund R, Forteza MJ, Ketelhuth DFJ, Butovsky O, Jagodic M, Zhang XM, Harris RA. Lund H, et al. Among authors: ewing e. Nat Immunol. 2018 May;19(5):1-7. doi: 10.1038/s41590-018-0091-5. Epub 2018 Apr 16. Nat Immunol. 2018. PMID: 29662171 Free PMC article.
DNA methylation as a mediator of HLA-DRB1*15:01 and a protective variant in multiple sclerosis.
Kular L, Liu Y, Ruhrmann S, Zheleznyakova G, Marabita F, Gomez-Cabrero D, James T, Ewing E, Lindén M, Górnikiewicz B, Aeinehband S, Stridh P, Link J, Andlauer TFM, Gasperi C, Wiendl H, Zipp F, Gold R, Tackenberg B, Weber F, Hemmer B, Strauch K, Heilmann-Heimbach S, Rawal R, Schminke U, Schmidt CO, Kacprowski T, Franke A, Laudes M, Dilthey AT, Celius EG, Søndergaard HB, Tegnér J, Harbo HF, Oturai AB, Olafsson S, Eggertsson HP, Halldorsson BV, Hjaltason H, Olafsson E, Jonsdottir I, Stefansson K, Olsson T, Piehl F, Ekström TJ, Kockum I, Feinberg AP, Jagodic M. Kular L, et al. Among authors: ewing e. Nat Commun. 2018 Jun 19;9(1):2397. doi: 10.1038/s41467-018-04732-5. Nat Commun. 2018. PMID: 29921915 Free PMC article.
Non-parametric combination analysis of multiple data types enables detection of novel regulatory mechanisms in T cells of multiple sclerosis patients.
Fernandes SJ, Morikawa H, Ewing E, Ruhrmann S, Joshi RN, Lagani V, Karathanasis N, Khademi M, Planell N, Schmidt A, Tsamardinos I, Olsson T, Piehl F, Kockum I, Jagodic M, Tegnér J, Gomez-Cabrero D. Fernandes SJ, et al. Among authors: ewing e. Sci Rep. 2019 Aug 19;9(1):11996. doi: 10.1038/s41598-019-48493-7. Sci Rep. 2019. PMID: 31427643 Free PMC article.
130 results