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SINEUPs: a novel toolbox for RNA therapeutics.
Espinoza S, Bon C, Valentini P, Pierattini B, Matey AT, Damiani D, Pulcrano S, Sanges R, Persichetti F, Takahashi H, Carninci P, Santoro C, Cotella D, Gustincich S. Espinoza S, et al. Essays Biochem. 2021 Oct 27;65(4):775-789. doi: 10.1042/EBC20200114. Essays Biochem. 2021. PMID: 34623427 Free PMC article. Review.
Neuronal hemoglobin affects dopaminergic cells' response to stress.
Codrich M, Bertuzzi M, Russo R, Francescatto M, Espinoza S, Zentilin L, Giacca M, Cesselli D, Beltrami AP, Ascenzi P, Zucchelli S, Persichetti F, Leanza G, Gustincich S. Codrich M, et al. Among authors: espinoza s. Cell Death Dis. 2017 Jan 5;8(1):e2538. doi: 10.1038/cddis.2016.458. Cell Death Dis. 2017. PMID: 28055011 Free PMC article.
SINEUP non-coding RNAs rescue defective frataxin expression and activity in a cellular model of Friedreich's Ataxia.
Bon C, Luffarelli R, Russo R, Fortuni S, Pierattini B, Santulli C, Fimiani C, Persichetti F, Cotella D, Mallamaci A, Santoro C, Carninci P, Espinoza S, Testi R, Zucchelli S, Condò I, Gustincich S. Bon C, et al. Among authors: espinoza s. Nucleic Acids Res. 2019 Nov 18;47(20):10728-10743. doi: 10.1093/nar/gkz798. Nucleic Acids Res. 2019. PMID: 31584077 Free PMC article.
Towards SINEUP-based therapeutics: Design of an in vitro synthesized SINEUP RNA.
Valentini P, Pierattini B, Zacco E, Mangoni D, Espinoza S, Webster NA, Andrews B, Carninci P, Tartaglia GG, Pandolfini L, Gustincich S. Valentini P, et al. Among authors: espinoza s. Mol Ther Nucleic Acids. 2022 Feb 2;27:1092-1102. doi: 10.1016/j.omtn.2022.01.021. eCollection 2022 Mar 8. Mol Ther Nucleic Acids. 2022. PMID: 35228902 Free PMC article.
A Metabologenomic approach reveals alterations in the gut microbiota of a mouse model of Alzheimer's disease.
Favero F, Barberis E, Gagliardi M, Espinoza S, Contu L, Gustincich S, Boccafoschi F, Borsotti C, Lim D, Rubino V, Mignone F, Pasolli E, Manfredi M, Zucchelli S, Corà D, Corazzari M. Favero F, et al. Among authors: espinoza s. PLoS One. 2022 Aug 24;17(8):e0273036. doi: 10.1371/journal.pone.0273036. eCollection 2022. PLoS One. 2022. PMID: 36001607 Free PMC article.
Neuronal haemoglobin induces loss of dopaminergic neurons in mouse Substantia nigra, cognitive deficits and cleavage of endogenous α-synuclein.
Santulli C, Bon C, De Cecco E, Codrich M, Narkiewicz J, Parisse P, Perissinotto F, Santoro C, Persichetti F, Legname G, Espinoza S, Gustincich S. Santulli C, et al. Among authors: espinoza s. Cell Death Dis. 2022 Dec 16;13(12):1048. doi: 10.1038/s41419-022-05489-y. Cell Death Dis. 2022. PMID: 36526614 Free PMC article.
255 results