Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

Search Results

178 results

Filters applied: . Clear all
Results are displayed in a computed author sort order. The Results By Year timeline is not available.
Page 1
Further understanding the connection between Alzheimer's disease and Down syndrome.
Snyder HM, Bain LJ, Brickman AM, Carrillo MC, Esbensen AJ, Espinosa JM, Fernandez F, Fortea J, Hartley SL, Head E, Hendrix J, Kishnani PS, Lai F, Lao P, Lemere C, Mobley W, Mufson EJ, Potter H, Zaman SH, Granholm AC, Rosas HD, Strydom A, Whitten MS, Rafii MS. Snyder HM, et al. Among authors: espinosa jm. Alzheimers Dement. 2020 Jul;16(7):1065-1077. doi: 10.1002/alz.12112. Epub 2020 Jun 16. Alzheimers Dement. 2020. PMID: 32544310 Free PMC article. Review.
Exosomal biomarkers in Down syndrome and Alzheimer's disease.
Hamlett ED, Ledreux A, Potter H, Chial HJ, Patterson D, Espinosa JM, Bettcher BM, Granholm AC. Hamlett ED, et al. Among authors: espinosa jm. Free Radic Biol Med. 2018 Jan;114:110-121. doi: 10.1016/j.freeradbiomed.2017.08.028. Epub 2017 Sep 5. Free Radic Biol Med. 2018. PMID: 28882786 Free PMC article. Review.
Trisomy 21 activates the kynurenine pathway via increased dosage of interferon receptors.
Powers RK, Culp-Hill R, Ludwig MP, Smith KP, Waugh KA, Minter R, Tuttle KD, Lewis HC, Rachubinski AL, Granrath RE, Carmona-Iragui M, Wilkerson RB, Kahn DE, Joshi M, Lleó A, Blesa R, Fortea J, D'Alessandro A, Costello JC, Sullivan KD, Espinosa JM. Powers RK, et al. Among authors: espinosa jm. Nat Commun. 2019 Oct 18;10(1):4766. doi: 10.1038/s41467-019-12739-9. Nat Commun. 2019. PMID: 31628327 Free PMC article.
Down Syndrome and COVID-19: A Perfect Storm?
Espinosa JM. Espinosa JM. Cell Rep Med. 2020 May 19;1(2):100019. doi: 10.1016/j.xcrm.2020.100019. Epub 2020 May 1. Cell Rep Med. 2020. PMID: 32501455 Free PMC article. Review.
IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome.
Araya P, Kinning KT, Coughlan C, Smith KP, Granrath RE, Enriquez-Estrada BA, Worek K, Sullivan KD, Rachubinski AL, Wolter-Warmerdam K, Hickey F, Galbraith MD, Potter H, Espinosa JM. Araya P, et al. Among authors: espinosa jm. Cell Rep. 2022 Dec 27;41(13):111883. doi: 10.1016/j.celrep.2022.111883. Cell Rep. 2022. PMID: 36577365 Free PMC article.
Red blood cell metabolism in Down syndrome: hints on metabolic derangements in aging.
Culp-Hill R, Zheng C, Reisz JA, Smith K, Rachubinski A, Nemkov T, Butcher E, Granrath R, Hansen KC, Espinosa JM, D'Alessandro A. Culp-Hill R, et al. Among authors: espinosa jm. Blood Adv. 2017 Dec 21;1(27):2776-2780. doi: 10.1182/bloodadvances.2017011957. eCollection 2017 Dec 26. Blood Adv. 2017. PMID: 29296929 Free PMC article.
Mass Cytometry Reveals Global Immune Remodeling with Multi-lineage Hypersensitivity to Type I Interferon in Down Syndrome.
Waugh KA, Araya P, Pandey A, Jordan KR, Smith KP, Granrath RE, Khanal S, Butcher ET, Estrada BE, Rachubinski AL, McWilliams JA, Minter R, Dimasi T, Colvin KL, Baturin D, Pham AT, Galbraith MD, Bartsch KW, Yeager ME, Porter CC, Sullivan KD, Hsieh EW, Espinosa JM. Waugh KA, et al. Among authors: espinosa jm. Cell Rep. 2019 Nov 12;29(7):1893-1908.e4. doi: 10.1016/j.celrep.2019.10.038. Cell Rep. 2019. PMID: 31722205 Free PMC article. Clinical Trial.
Tumoural soft tissue calcification in Down syndrome: association with heterozygous germline SAMD9 mutation and hyperactive type I interferon signaling.
Deigendesch N, Hirsiger JR, Bigler MB, Ghosh A, Harder D, Jauch A, Espinosa JM, Recher M, Navarini A, Daikeler T, Berger CT. Deigendesch N, et al. Among authors: espinosa jm. Rheumatology (Oxford). 2020 Nov 1;59(11):e102-e104. doi: 10.1093/rheumatology/keaa301. Rheumatology (Oxford). 2020. PMID: 32594144 Free PMC article. No abstract available.
JAK1 Inhibition Blocks Lethal Immune Hypersensitivity in a Mouse Model of Down Syndrome.
Tuttle KD, Waugh KA, Araya P, Minter R, Orlicky DJ, Ludwig M, Andrysik Z, Burchill MA, Tamburini BAJ, Sempeck C, Smith K, Granrath R, Tracy D, Baxter J, Espinosa JM, Sullivan KD. Tuttle KD, et al. Among authors: espinosa jm. Cell Rep. 2020 Nov 17;33(7):108407. doi: 10.1016/j.celrep.2020.108407. Cell Rep. 2020. PMID: 33207208 Free PMC article.
178 results