Espadinha M - Search Results

1

Hybrid molecules of protoflavones and spirooxindole derivatives with selective cytotoxicity against triple-negative breast cancer cells.

Girst G, Lopes EA, Gonçalves LM, Espadinha M, Kúsz N, Wang HC, Santos MMM, Hunyadi A. Girst G, et al. Among authors: espadinha m. RSC Med Chem. 2023 Aug 1;14(9):1778-1786. doi: 10.1039/d3md00251a. eCollection 2023 Sep 19. RSC Med Chem. 2023. PMID: 37731691 Free PMC article.

2

Novel squaramides with in vitro liver stage antiplasmodial activity.

Ribeiro CJ, Espadinha M, Machado M, Gut J, Gonçalves LM, Rosenthal PJ, Prudêncio M, Moreira R, Santos MM. Ribeiro CJ, et al. Among authors: espadinha m. Bioorg Med Chem. 2016 Apr 15;24(8):1786-92. doi: 10.1016/j.bmc.2016.03.005. Epub 2016 Mar 3. Bioorg Med Chem. 2016. PMID: 26968650

3

An Update on MDMX and Dual MDM2/X Inhibitors.

Espadinha M, Barcherini V, Lopes EA, Santos MMM. Espadinha M, et al. Curr Top Med Chem. 2018;18(8):647-660. doi: 10.2174/1568026618666180604080119. Curr Top Med Chem. 2018. PMID: 29866007 Review.

4

Exploiting the antiproliferative potential of spiropyrazoline oxindoles in a human ovarian cancer cell line.

Raposo LR, Silva A, Silva D, Roma-Rodrigues C, Espadinha M, Baptista PV, Santos MMM, Fernandes AR. Raposo LR, et al. Among authors: espadinha m. Bioorg Med Chem. 2021 Jan 15;30:115880. doi: 10.1016/j.bmc.2020.115880. Epub 2020 Dec 15. Bioorg Med Chem. 2021. PMID: 33348171

5

Tryptophanol-Derived Oxazolopyrrolidone Lactams as Potential Anticancer Agents against Gastric Adenocarcinoma.

Espadinha M, Barcherini V, Gonçalves LM, Molins E, Antunes AMM, Santos MMM. Espadinha M, et al. Pharmaceuticals (Basel). 2021 Mar 2;14(3):208. doi: 10.3390/ph14030208. Pharmaceuticals (Basel). 2021. PMID: 33801507 Free PMC article.

6

Discovery of MDM2-p53 and MDM4-p53 protein-protein interactions small molecule dual inhibitors.

Espadinha M, Lopes EA, Marques V, Amaral JD, Dos Santos DJVA, Mori M, Daniele S, Piccarducci R, Zappelli E, Martini C, Rodrigues CMP, Santos MMM. Espadinha M, et al. Eur J Med Chem. 2022 Nov 5;241:114637. doi: 10.1016/j.ejmech.2022.114637. Epub 2022 Aug 5. Eur J Med Chem. 2022. PMID: 35961068 Free article.

7

Indolo[2,3-a]quinolizidines and Derivatives: Bioactivity and Asymmetric Synthesis.

Perez M, Espadinha M, Santos MM. Perez M, et al. Among authors: espadinha m. Curr Pharm Des. 2015;21(38):5518-46. doi: 10.2174/1381612821666151002112934. Curr Pharm Des. 2015. PMID: 26429714 Free article. Review.

8

Identification of tetracyclic lactams as NMDA receptor antagonists with potential application in neurological disorders.

Espadinha M, Viejo L, Lopes RMRM, Herrera-Arozamena C, Molins E, Dos Santos DJVA, Gonçalves L, Rodríguez-Franco MI, Ríos CL, Santos MMM. Espadinha M, et al. Eur J Med Chem. 2020 May 15;194:112242. doi: 10.1016/j.ejmech.2020.112242. Epub 2020 Mar 23. Eur J Med Chem. 2020. PMID: 32248004

9

Optimization of Bicyclic Lactam Derivatives as NMDA Receptor Antagonists.

Espadinha M, Dourado J, Lajarin-Cuesta R, Herrera-Arozamena C, Gonçalves LM, Rodríguez-Franco MI, de Los Rios C, Santos MM. Espadinha M, et al. ChemMedChem. 2017 Apr 6;12(7):537-545. doi: 10.1002/cmdc.201700037. Epub 2017 Mar 22. ChemMedChem. 2017. PMID: 28218498 Free article.

10

Improving anticancer activity towards colon cancer cells with a new p53-activating agent.

Raimundo L, Espadinha M, Soares J, Loureiro JB, Alves MG, Santos MMM, Saraiva L. Raimundo L, et al. Among authors: espadinha m. Br J Pharmacol. 2018 Oct;175(20):3947-3962. doi: 10.1111/bph.14468. Epub 2018 Sep 6. Br J Pharmacol. 2018. PMID: 30076608 Free PMC article.

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