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Application of evidence-based methods to construct mechanism-driven chemical assessment frameworks.
Hoffmann S, Aiassa E, Angrish M, Beausoleil C, Bois FY, Ciccolallo L, Craig PS, De Vries RBM, Dorne JLCM, Druwe IL, Edwards SW, Eskes C, Georgiadis M, Hartung T, Kienzler A, Kristjansson EA, Lam J, Martino L, Meek B, Morgan RL, Munoz-Guajardo I, Noyes PD, Parmelli E, Piersma A, Rooney A, Sena E, Sullivan K, Tarazona J, Terron A, Thayer K, Turner J, Verbeek J, Verloo D, Vinken M, Watford S, Whaley P, Wikoff D, Willett K, Tsaioun K. Hoffmann S, et al. Among authors: eskes c. ALTEX. 2022;39(3):499–518. doi: 10.14573/altex.2202141. Epub 2022 Mar 1. ALTEX. 2022. PMID: 35258090 Free PMC article.
Integrated Testing Strategies (ITS) for safety assessment.
Rovida C, Alépée N, Api AM, Basketter DA, Bois FY, Caloni F, Corsini E, Daneshian M, Eskes C, Ezendam J, Fuchs H, Hayden P, Hegele-Hartung C, Hoffmann S, Hubesch B, Jacobs MN, Jaworska J, Kleensang A, Kleinstreuer N, Lalko J, Landsiedel R, Lebreux F, Luechtefeld T, Locatelli M, Mehling A, Natsch A, Pitchford JW, Prater D, Prieto P, Schepky A, Schüürmann G, Smirnova L, Toole C, van Vliet E, Weisensee D, Hartung T. Rovida C, et al. Among authors: eskes c. ALTEX. 2015;32(1):25-40. doi: 10.14573/altex.1411011. Epub 2014 Nov 19. ALTEX. 2015. PMID: 25413849 Free article.
Workshop on the validation and regulatory acceptance of innovative 3R approaches in regulatory toxicology - Evolution versus revolution.
Burgdorf T, Piersma AH, Landsiedel R, Clewell R, Kleinstreuer N, Oelgeschläger M, Desprez B, Kienhuis A, Bos P, de Vries R, de Wit L, Seidle T, Scheel J, Schönfelder G, van Benthem J, Vinggaard AM, Eskes C, Ezendam J. Burgdorf T, et al. Among authors: eskes c. Toxicol In Vitro. 2019 Sep;59:1-11. doi: 10.1016/j.tiv.2019.03.039. Epub 2019 Apr 1. Toxicol In Vitro. 2019. PMID: 30946968
Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems.
Pamies D, Bal-Price A, Chesné C, Coecke S, Dinnyes A, Eskes C, Grillari R, Gstraunthaler G, Hartung T, Jennings P, Leist M, Martin U, Passier R, Schwamborn JC, Stacey GN, Ellinger-Ziegelbauer H, Daneshian M. Pamies D, et al. Among authors: eskes c. ALTEX. 2018;35(3):353-378. doi: 10.14573/altex.1710081. Epub 2018 Apr 13. ALTEX. 2018. PMID: 29697851 Free article.
Workshop on acceleration of the validation and regulatory acceptance of alternative methods and implementation of testing strategies.
Piersma AH, Burgdorf T, Louekari K, Desprez B, Taalman R, Landsiedel R, Barroso J, Rogiers V, Eskes C, Oelgeschläger M, Whelan M, Braeuning A, Vinggaard AM, Kienhuis A, van Benthem J, Ezendam J. Piersma AH, et al. Among authors: eskes c. Toxicol In Vitro. 2018 Aug;50:62-74. doi: 10.1016/j.tiv.2018.02.018. Epub 2018 Mar 2. Toxicol In Vitro. 2018. PMID: 29501630 Free article.
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing.
Basketter DA, Clewell H, Kimber I, Rossi A, Blaauboer B, Burrier R, Daneshian M, Eskes C, Goldberg A, Hasiwa N, Hoffmann S, Jaworska J, Knudsen TB, Landsiedel R, Leist M, Locke P, Maxwell G, McKim J, McVey EA, Ouédraogo G, Patlewicz G, Pelkonen O, Roggen E, Rovida C, Ruhdel I, Schwarz M, Schepky A, Schoeters G, Skinner N, Trentz K, Turner M, Vanparys P, Yager J, Zurlo J, Hartung T. Basketter DA, et al. Among authors: eskes c. ALTEX. 2012;29(1):3-91. doi: 10.14573/altex.2012.1.003. ALTEX. 2012. PMID: 22307314
Good cell culture practices &in vitro toxicology.
Eskes C, Boström AC, Bowe G, Coecke S, Hartung T, Hendriks G, Pamies D, Piton A, Rovida C. Eskes C, et al. Toxicol In Vitro. 2017 Dec;45(Pt 3):272-277. doi: 10.1016/j.tiv.2017.04.022. Epub 2017 Apr 25. Toxicol In Vitro. 2017. PMID: 28450071
52 results