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IVT generation of guideRNAs for Cas9-enrichment Nanopore Sequencing.
Gilpatrick T, Wang JZ, Weiss D, Norris AL, Eshleman J, Timp W. Gilpatrick T, et al. Among authors: eshleman j. bioRxiv [Preprint]. 2023 Feb 7:2023.02.07.527484. doi: 10.1101/2023.02.07.527484. bioRxiv. 2023. PMID: 36798399 Free PMC article. Preprint.
Whole genomes redefine the mutational landscape of pancreatic cancer.
Waddell N, Pajic M, Patch AM, Chang DK, Kassahn KS, Bailey P, Johns AL, Miller D, Nones K, Quek K, Quinn MC, Robertson AJ, Fadlullah MZ, Bruxner TJ, Christ AN, Harliwong I, Idrisoglu S, Manning S, Nourse C, Nourbakhsh E, Wani S, Wilson PJ, Markham E, Cloonan N, Anderson MJ, Fink JL, Holmes O, Kazakoff SH, Leonard C, Newell F, Poudel B, Song S, Taylor D, Waddell N, Wood S, Xu Q, Wu J, Pinese M, Cowley MJ, Lee HC, Jones MD, Nagrial AM, Humphris J, Chantrill LA, Chin V, Steinmann AM, Mawson A, Humphrey ES, Colvin EK, Chou A, Scarlett CJ, Pinho AV, Giry-Laterriere M, Rooman I, Samra JS, Kench JG, Pettitt JA, Merrett ND, Toon C, Epari K, Nguyen NQ, Barbour A, Zeps N, Jamieson NB, Graham JS, Niclou SP, Bjerkvig R, Grützmann R, Aust D, Hruban RH, Maitra A, Iacobuzio-Donahue CA, Wolfgang CL, Morgan RA, Lawlor RT, Corbo V, Bassi C, Falconi M, Zamboni G, Tortora G, Tempero MA; Australian Pancreatic Cancer Genome Initiative; Gill AJ, Eshleman JR, Pilarsky C, Scarpa A, Musgrove EA, Pearson JV, Biankin AV, Grimmond SM. Waddell N, et al. Among authors: eshleman jr. Nature. 2015 Feb 26;518(7540):495-501. doi: 10.1038/nature14169. Nature. 2015. PMID: 25719666 Free PMC article.
[No title available]
[No authors listed] [No authors listed] PMID: 38353794
Epigenetic control of multiple genes with a lentiviral vector encoding transcriptional repressors fused to compact zinc finger arrays.
Monteferrario D, David M, Tadi SK, Zhou Y, Marchetti I, Jeanneau C, Saviane G, Dupont CF, Martelli AE, Truong LN, Eshleman JA, Ng CC, Huston MW, Davis GD, Fontenot JD, Reik A, Rosa M, Fenard D. Monteferrario D, et al. Among authors: eshleman ja. Mol Ther Methods Clin Dev. 2024 Apr 24;32(2):101255. doi: 10.1016/j.omtm.2024.101255. eCollection 2024 Jun 13. Mol Ther Methods Clin Dev. 2024. PMID: 38715734 Free PMC article.
Using Tumor Marker Gene Variants to Improve the Diagnostic Accuracy of DUPAN-2 and Carbohydrate Antigen 19-9 for Pancreatic Cancer.
Ando Y, Dbouk M, Yoshida T, Saba H, Abou Diwan E, Yoshida K, Dbouk A, Blackford AL, Lin MT, Lennon AM, Burkhart RA, He J, Sokoll L, Eshleman JR, Canto MI, Goggins M. Ando Y, et al. Among authors: eshleman jr. J Clin Oncol. 2024 Mar 8:JCO2301573. doi: 10.1200/JCO.23.01573. Online ahead of print. J Clin Oncol. 2024. PMID: 38457748
Compact zinc finger architecture utilizing toxin-derived cytidine deaminases for highly efficient base editing in human cells.
Fauser F, Kadam BN, Arangundy-Franklin S, Davis JE, Vaidya V, Schmidt NJ, Lew G, Xia DF, Mureli R, Ng C, Zhou Y, Scarlott NA, Eshleman J, Bendaña YR, Shivak DA, Reik A, Li P, Davis GD, Miller JC. Fauser F, et al. Among authors: eshleman j. Nat Commun. 2024 Feb 15;15(1):1181. doi: 10.1038/s41467-024-45100-w. Nat Commun. 2024. PMID: 38360922 Free PMC article.
Islands of genomic stability in the face of genetically unstable metastatic cancer.
Bowland K, Lai J, Skaist A, Zhang Y, Teh SSK, Roberts NJ, Thompson E, Wheelan SJ, Hruban RH, Karchin R, Iacobuzio-Donahue CA, Eshleman JR. Bowland K, et al. Among authors: eshleman jr. bioRxiv [Preprint]. 2024 Jan 29:2024.01.26.577508. doi: 10.1101/2024.01.26.577508. bioRxiv. 2024. PMID: 38352348 Free PMC article. Preprint.
A first-in-class pan-lysyl oxidase inhibitor impairs stromal remodeling and enhances gemcitabine response and survival in pancreatic cancer.
Chitty JL, Yam M, Perryman L, Parker AL, Skhinas JN, Setargew YFI, Mok ETY, Tran E, Grant RD, Latham SL, Pereira BA, Ritchie SC, Murphy KJ, Trpceski M, Findlay AD, Melenec P, Filipe EC, Nadalini A, Velayuthar S, Major G, Wyllie K, Papanicolaou M, Ratnaseelan S, Phillips PA, Sharbeen G, Youkhana J, Russo A, Blackwell A, Hastings JF, Lucas MC, Chambers CR, Reed DA, Stoehr J, Vennin C, Pidsley R, Zaratzian A, Da Silva AM, Tayao M, Charlton B, Herrmann D, Nobis M, Clark SJ, Biankin AV, Johns AL, Croucher DR, Nagrial A, Gill AJ, Grimmond SM; Australian Pancreatic Cancer Genome Initiative (APGI); Australian Pancreatic Cancer Matrix Atlas (APMA); Pajic M, Timpson P, Jarolimek W, Cox TR. Chitty JL, et al. Nat Cancer. 2023 Sep;4(9):1326-1344. doi: 10.1038/s43018-023-00614-y. Epub 2023 Aug 28. Nat Cancer. 2023. PMID: 37640930 Free PMC article.
313 results