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Deleterious Effect of p-Cresol on Human Colonic Epithelial Cells Prevented by Proanthocyanidin-Containing Polyphenol Extracts from Fruits and Proanthocyanidin Bacterial Metabolites.
Wong X, Carrasco-Pozo C, Escobar E, Navarrete P, Blachier F, Andriamihaja M, Lan A, Tomé D, Cires MJ, Pastene E, Gotteland M. Wong X, et al. Among authors: escobar e. J Agric Food Chem. 2016 May 11;64(18):3574-83. doi: 10.1021/acs.jafc.6b00656. Epub 2016 May 2. J Agric Food Chem. 2016. PMID: 27039931 Free article.
Vitamin C is an essential antioxidant that enhances survival of oxidatively stressed human vascular endothelial cells in the presence of a vast molar excess of glutathione.
Montecinos V, Guzmán P, Barra V, Villagrán M, Muñoz-Montesino C, Sotomayor K, Escobar E, Godoy A, Mardones L, Sotomayor P, Guzmán C, Vásquez O, Gallardo V, van Zundert B, Bono MR, Oñate SA, Bustamante M, Cárcamo JG, Rivas CI, Vera JC. Montecinos V, et al. Among authors: escobar e. J Biol Chem. 2007 May 25;282(21):15506-15. doi: 10.1074/jbc.M608361200. Epub 2007 Apr 2. J Biol Chem. 2007. PMID: 17403685 Free article.
Histidine residues in the Na+-coupled ascorbic acid transporter-2 (SVCT2) are central regulators of SVCT2 function, modulating pH sensitivity, transporter kinetics, Na+ cooperativity, conformational stability, and subcellular localization.
Ormazabal V, Zuñiga FA, Escobar E, Aylwin C, Salas-Burgos A, Godoy A, Reyes AM, Vera JC, Rivas CI. Ormazabal V, et al. Among authors: escobar e. J Biol Chem. 2010 Nov 19;285(47):36471-85. doi: 10.1074/jbc.M110.155630. Epub 2010 Sep 14. J Biol Chem. 2010. PMID: 20843809 Free PMC article.
Sustained blockade of ascorbic acid transport associated with marked SVCT1 loss in rat hepatocytes containing increased ascorbic acid levels after partial hepatectomy.
Maldonado M, Inostroza E, Peña E, Moncada N, Mardones L, Medina JL, Muñoz A, Gatica M, Villagrán M, Escobar E, Mendoza P, Roa FJ, González M, Guzmán P, Gutiérrez-Castro FA, Sweet K, Muñoz-Montesino C, Vera JC, Rivas CI. Maldonado M, et al. Among authors: escobar e. Free Radic Biol Med. 2017 Jul;108:655-667. doi: 10.1016/j.freeradbiomed.2017.04.006. Epub 2017 Apr 15. Free Radic Biol Med. 2017. PMID: 28419867
Transport of Vitamin C in Cancer.
Muñoz-Montesino C, Peña E, Roa FJ, Sotomayor K, Escobar E, Rivas CI. Muñoz-Montesino C, et al. Among authors: escobar e. Antioxid Redox Signal. 2021 Jul;35(1):61-74. doi: 10.1089/ars.2020.8166. Epub 2021 Apr 23. Antioxid Redox Signal. 2021. PMID: 33607936 Review.
Cis-regulatory elements involved in species-specific transcriptional regulation of the SVCT1 gene in rat and human hepatoma cells.
Muñoz A, Villagrán M, Guzmán P, Solíz C, Gatica M, Aylwin C, Sweet K, Maldonado M, Escobar E, Reyes AM, Toledo JR, Sánchez O, Oñate SA, Carlos Vera J, Rivas CI. Muñoz A, et al. Among authors: escobar e. Free Radic Biol Med. 2015 Aug;85:183-96. doi: 10.1016/j.freeradbiomed.2015.04.024. Epub 2015 Apr 28. Free Radic Biol Med. 2015. PMID: 25933589
Aggregation of α- and β- caseins induced by peroxyl radicals involves secondary reactions of carbonyl compounds as well as di-tyrosine and di-tryptophan formation.
Fuentes-Lemus E, Silva E, Barrias P, Aspee A, Escobar E, Lorentzen LG, Carroll L, Leinisch F, Davies MJ, López-Alarcón C. Fuentes-Lemus E, et al. Among authors: escobar e. Free Radic Biol Med. 2018 Aug 20;124:176-188. doi: 10.1016/j.freeradbiomed.2018.06.005. Epub 2018 Jun 7. Free Radic Biol Med. 2018. PMID: 29885785
273 results