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2-Sulfonamidopyridine C-region analogs of 2-(3-fluoro-4-methylsulfonamidophenyl)propanamides as potent TRPV1 antagonists.
Ann J, Ki Y, Yoon S, Kim MS, Lee JU, Kim C, Lee S, Jung A, Baek J, Hong S, Choi S, Pearce LV, Esch TE, Turcios NA, Lewin NE, Ogunjirin AE, Herold BK, McCall AK, Blumberg PM, Lee J. Ann J, et al. Among authors: esch te. Bioorg Med Chem. 2016 Mar 15;24(6):1231-40. doi: 10.1016/j.bmc.2016.01.051. Epub 2016 Jan 28. Bioorg Med Chem. 2016. PMID: 26860926 Free PMC article.
Asymmetric synthesis and receptor activity of chiral simplified resiniferatoxin (sRTX) analogues as transient receptor potential vanilloid 1 (TRPV1) ligands.
Kim MS, Ki Y, Ahn SY, Yoon S, Kim SE, Park HG, Sun W, Son K, Cui M, Choi S, Pearce LV, Esch TE, Deandrea-Lazarus IA, Blumberg PM, Lee J. Kim MS, et al. Among authors: esch te. Bioorg Med Chem Lett. 2014 Jan 1;24(1):382-5. doi: 10.1016/j.bmcl.2013.10.064. Epub 2013 Nov 6. Bioorg Med Chem Lett. 2014. PMID: 24321344 Free PMC article.
Discovery of N-(3-fluoro-4-methylsulfonamidomethylphenyl)urea as a potent TRPV1 antagonistic template.
Ann J, Sun W, Zhou X, Jung A, Baek J, Lee S, Kim C, Yoon S, Hong S, Choi S, Turcios NA, Herold BK, Esch TE, Lewin NE, Abramovitz A, Pearce LV, Blumberg PM, Lee J. Ann J, et al. Among authors: esch te. Bioorg Med Chem Lett. 2016 Aug 1;26(15):3603-7. doi: 10.1016/j.bmcl.2016.06.010. Epub 2016 Jun 7. Bioorg Med Chem Lett. 2016. PMID: 27317643 Free PMC article.
Discovery of Benzopyridone-Based Transient Receptor Potential Vanilloid 1 Agonists and Antagonists and the Structural Elucidation of Their Activity Shift.
Thorat SA, Lee Y, Jung A, Ann J, Ahn S, Baek J, Zuo D, Do N, Jeong JJ, Blumberg PM, Esch TE, Turcios NA, Pearce LV, Ha HJ, Yoo YD, Hong S, Choi S, Lee J. Thorat SA, et al. Among authors: esch te. J Med Chem. 2021 Jan 14;64(1):370-384. doi: 10.1021/acs.jmedchem.0c00982. Epub 2021 Jan 1. J Med Chem. 2021. PMID: 33385210
Synthesis, biological, and biophysical studies of DAG-indololactones designed as selective activators of RasGRP.
Garcia LC, Donadío LG, Mann E, Kolusheva S, Kedei N, Lewin NE, Hill CS, Kelsey JS, Yang J, Esch TE, Santos M, Peach ML, Kelley JA, Blumberg PM, Jelinek R, Marquez VE, Comin MJ. Garcia LC, et al. Among authors: esch te. Bioorg Med Chem. 2014 Jun 15;22(12):3123-40. doi: 10.1016/j.bmc.2014.04.024. Epub 2014 Apr 20. Bioorg Med Chem. 2014. PMID: 24794745 Free PMC article.
RasGRPs are targets of the anti-cancer agent ingenol-3-angelate.
Song X, Lopez-Campistrous A, Sun L, Dower NA, Kedei N, Yang J, Kelsey JS, Lewin NE, Esch TE, Blumberg PM, Stone JC. Song X, et al. Among authors: esch te. PLoS One. 2013 Aug 21;8(8):e72331. doi: 10.1371/journal.pone.0072331. eCollection 2013. PLoS One. 2013. PMID: 23991094 Free PMC article.
Combined Measurement of the Higgs Boson Mass in pp Collisions at sqrt[s]=7 and 8 TeV with the ATLAS and CMS Experiments.
Aad G, Abbott B, Abdallah J, Abdinov O, Aben R, Abolins M, AbouZeid OS, Abramowicz H, Abreu H, Abreu R, Abulaiti Y, Acharya BS, Adamczyk L, Adams DL, Adelman J, Adomeit S, Adye T, Affolder AA, Agatonovic-Jovin T, Aguilar-Saavedra JA, Ahlen SP, Ahmadov F, Aielli G, Akerstedt H, Åkesson TP, Akimoto G, Akimov AV, Alberghi GL, Albert J, Albrand S, Alconada Verzini MJ, Aleksa M, Aleksandrov IN, Alexa C, Alexander G, Alexopoulos T, Alhroob M, Alimonti G, Alio L, Alison J, Alkire SP, Allbrooke BM, Allport PP, Aloisio A, Alonso A, Alonso F, Alpigiani C, Altheimer A, Alvarez Gonzalez B, Álvarez Piqueras D, Alviggi MG, Amadio BT, Amako K, Amaral Coutinho Y, Amelung C, Amidei D, Amor Dos Santos SP, Amorim A, Amoroso S, Amram N, Amundsen G, Anastopoulos C, Ancu LS, Andari N, Andeen T, Anders CF, Anders G, Anders JK, Anderson KJ, Andreazza A, Andrei V, Angelidakis S, Angelozzi I, Anger P, Angerami A, Anghinolfi F, Anisenkov AV, Anjos N, Annovi A, Antonelli M, Antonov A, Antos J, Anulli F, Aoki M, Aperio Bella L, Arabidze G, Arai Y, Araque JP, Arce AT, Arduh FA, Arguin JF, Argyropoulos S, Arik M, Armbruster AJ, Arnaez O, Arnal V, Arnold H, Arratia M, Arslan O, Artamonov A, Artoni G, Asai S, Asb… See abstract for full author list ➔ Aad G, et al. Phys Rev Lett. 2015 May 15;114(19):191803. doi: 10.1103/PhysRevLett.114.191803. Epub 2015 May 14. Phys Rev Lett. 2015. PMID: 26024162 Free article.
Study of B Meson Production in p+Pb Collisions at √[S(NN)]=5.02 TeV Using Exclusive Hadronic Decays.
Khachatryan V, Sirunyan AM, Tumasyan A, Adam W, Asilar E, Bergauer T, Brandstetter J, Brondolin E, Dragicevic M, Erö J, Flechl M, Friedl M, Frühwirth R, Ghete VM, Hartl C, Hörmann N, Hrubec J, Jeitler M, Knünz V, König A, Krammer M, Krätschmer I, Liko D, Matsushita T, Mikulec I, Rabady D, Rahbaran B, Rohringer H, Schieck J, Schöfbeck R, Strauss J, Treberer-Treberspurg W, Waltenberger W, Wulz CE, Mossolov V, Shumeiko N, Suarez Gonzalez J, Alderweireldt S, Cornelis T, De Wolf EA, Janssen X, Knutsson A, Lauwers J, Luyckx S, Ochesanu S, Rougny R, Van De Klundert M, Van Haevermaet H, Van Mechelen P, Van Remortel N, Van Spilbeeck A, Abu Zeid S, Blekman F, D'Hondt J, Daci N, De Bruyn I, Deroover K, Heracleous N, Keaveney J, Lowette S, Moreels L, Olbrechts A, Python Q, Strom D, Tavernier S, Van Doninck W, Van Mulders P, Van Onsem GP, Van Parijs I, Barria P, Brun H, Caillol C, Clerbaux B, De Lentdecker G, Delannoy H, Fasanella G, Favart L, Gay AP, Grebenyuk A, Karapostoli G, Lenzi T, Léonard A, Maerschalk T, Marinov A, Perniè L, Randle-Conde A, Reis T, Seva T, Vander Velde C, Vanlaer P, Yonamine R, Zenoni F, Zhang F, Beernaert K, Benucci L, Cimmino A, Crucy S, Dobur D, Fagot A, Garcia G, G… See abstract for full author list ➔ Khachatryan V, et al. Phys Rev Lett. 2016 Jan 22;116(3):032301. doi: 10.1103/PhysRevLett.116.032301. Epub 2016 Jan 22. Phys Rev Lett. 2016. PMID: 26849587 Free article.
144 results