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Treatment response of advanced HNSCC towards immune checkpoint inhibition is associated with an activated effector memory T cell phenotype.
Front Oncol. 2024 Mar 7;14:1333640. doi: 10.3389/fonc.2024.1333640. eCollection 2024.
Front Oncol. 2024.
PMID: 38515578
Free PMC article.
The RORɣ/SREBP2 pathway is a master regulator of cholesterol metabolism and serves as potential therapeutic target in t(4;11) leukemia.
Erkner E, Hentrich T, Schairer R, Fitzel R, Secker-Grob KA, Jeong J, Keppeler H, Korkmaz F, Schulze-Hentrich JM, Lengerke C, Schneidawind D, Schneidawind C.
Erkner E, et al.
Oncogene. 2024 Jan;43(4):281-293. doi: 10.1038/s41388-023-02903-3. Epub 2023 Nov 29.
Oncogene. 2024.
PMID: 38030791
Free PMC article.
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Uncovering NOTCH1 as a Promising Target in the Treatment of MLL-Rearranged Leukemia.
Fischer J, Erkner E, Fitzel R, Radszuweit P, Keppeler H, Korkmaz F, Roti G, Lengerke C, Schneidawind D, Schneidawind C.
Fischer J, et al. Among authors: erkner e.
Int J Mol Sci. 2023 Sep 23;24(19):14466. doi: 10.3390/ijms241914466.
Int J Mol Sci. 2023.
PMID: 37833915
Free PMC article.
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Targeting MYC in combination with epigenetic regulators induces synergistic anti-leukemic effects in MLLr leukemia and simultaneously improves immunity.
Fitzel R, Secker-Grob KA, Keppeler H, Korkmaz F, Schairer R, Erkner E, Schneidawind D, Lengerke C, Hentrich T, Schulze-Hentrich JM, Schneidawind C.
Fitzel R, et al. Among authors: erkner e.
Neoplasia. 2023 Jul;41:100902. doi: 10.1016/j.neo.2023.100902. Epub 2023 May 4.
Neoplasia. 2023.
PMID: 37148657
Free PMC article.
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Cleavage of the vaspin N-terminus releases cell-penetrating peptides that affect early stages of adipogenesis and inhibit lipolysis in mature adipocytes.
Tindall CA, Erkner E, Stichel J, Beck-Sickinger AG, Hoffmann A, Weiner J, Heiker JT.
Tindall CA, et al. Among authors: erkner e.
Adipocyte. 2021 Dec;10(1):216-231. doi: 10.1080/21623945.2021.1910154.
Adipocyte. 2021.
PMID: 33866927
Free PMC article.
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